“…[8,9] Among various CAPs sources, atmospheric pressure plasma jets (APPJs) could be generated into the open air with a discharge gap instead of traditional discharge, low gas temperature, simple structure, convenient handing, and highly reactive chemical species are attracting considerable attention from many scholars and various types of APPJ devices have been reported. [10] Plasma jets can be classified into four categories: dielectric-free electrode (DFE) jets, dielectric barrier discharge (DBD) jets, DBDlike jets, and single electrode (SE) jets, [11] DBD is one of the most effective ways to produce CAPs, due to the limitation of the barrier medium on the discharge current, the discharge will not convert to arc has attracted extensive attention, [12,13] the electrode structure mainly has two forms: parallel plate-plate and coaxial rod-ring, its main feature is that the electrode gap is filled with a specific working gas, at the same time, at least one electrode is covered by an insulating medium or the insulating medium is fixed between the electrodes. [14,15] Needle-ring electrodes DBD plasma jet is one of the DBD-like jets, but needle-ring electrodes plasma jet with a solid electrode and hollow electrode in discharge characteristics and anticancer effects are not reported yet.…”