Enhanced antibacterial properties and the cellular response of stainless steel through friction stir processing

Perumal, G.; Chakrabarti, Amrita; Grewal, Harpreet Singh; Pati, Soumya; Singh, Shailja; Arora, Harpreet Singh

doi:10.1080/08927014.2019.1584794

Cited by 9 publications

(4 citation statements)

References 49 publications

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“…However, the nTi‐S MS curve yields higher slope with lower donor density value compared to Ti, whereas both n‐Ti and nTi‐PEG had higher donor density value. The significance of the same is discussed in the later section 39,56 …”

Section: Resultsmentioning

confidence: 91%

“…The significance of the same is discussed in the later section. 39,56 Cytotoxicity of different surfaces was characterized after 2 hr of incubation with PRP. PRP of human blood is made up of white blood cells and platelets is a simple model to study cytotoxicity.…”

Section: Resultsmentioning

confidence: 99%

“…Mott Schottky analysis was to analyze the surface charge of the passive layer formed on different surfaces 41 . Studies have shown that surface modifications can influence surface charge by altering charge carrier density and its Fermi level 56,64 . The significance of relative positioning of flat‐band potential with respect to OCP is key in predicting the surface charge of different surfaces.…”

Section: Discussionmentioning

confidence: 99%

“…41 Studies have shown that surface modifications can influence surface charge by altering charge carrier density and its Fermi level. 56,64 The significance of relative positioning of flatband potential with respect to OCP is key in predicting the surface charge of different surfaces. Further, studies have shown that decrease in donor density helps in increase in corrosion resistance due to lesser number of oxygen vacancies and interstitials titanium.…”

Section: Discussionmentioning

confidence: 99%

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Enhanced antibacterial properties on superhydrophobic micro‐nano structured titanium surface

Manivasagam

Perumal

Arora

et al. 2022

J Biomedical Materials Res

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Micro/nano scale surface modifications of titanium based orthopedic and cardiovascular implants has shown to augment biocompatibility. However, bacterial infection remains a serious concern for implant failure, aggravated by increasing antibiotic resistance and over usage of antibiotics. Bacteria cell adhesion on implant surface leads to colonization and biofilm formation resulting in morbidity and mortality. Hence, there is a need to develop new implant surfaces with high antibacterial properties. Recent developments have shown that superhydrophobic surfaces prevent protein and bacteria cell adhesion. In this study, a thermochemical treatment was used modify the surface properties for high efficacy antibacterial activity on titanium surface. The modification led to a micro‐nano surface topography and upon modification with polyethylene glycol (PEG) and silane the surfaces were superhydrophilic and superhydrophobic, respectively. The modified surfaces were characterized for morphology, wettability, chemistry, corrosion resistance and surface charge. The antibacterial capability was characterized with Staphylococcus aureus and Escherichia coli by evaluating the bacteria cell inhibition, adhesion kinetics, and biofilm formation. The results indicated that the superhydrophobic micro‐nano structured titanium surface reduced bacteria cell adhesion significantly (>90%) and prevented biofilm formation compared to the unmodified titanium surface after 24 h of incubation.

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Section: Resultsmentioning

confidence: 91%

Section: Resultsmentioning

confidence: 99%