Enhanced Antibacterial and Antibiofilm Activities of Actinobacterial Therapeutic Metabolites Mediated Nanosuspension
Shelly Singh,
Shilpa Sharma,
Ashok K. Dubey
Abstract:The escalation in infections from World Health Organization (WHO)‐listed priority pathogens has made development of new antibacterial agents a critical priority. In this context, use of therapeutic secondary metabolites (SMs) from Actinobacteria as new drugs presents a promising avenue. However, majority of them fail to reach market due to low aqueous solubility and hence low bioavailability. Even though nanosuspension technology has been effectively used to address these challenges, use of this technology for… Show more
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