Engineering Wet‐Resistant and Osteogenic Nanocomposite Adhesive to Control Bleeding and Infection after Median Sternotomy
Mahshid Shokri,
Mahshid Kharaziha,
Hossein Ahmadi Tafti
et al.
Abstract:Median sternotomy surgery stands as one of the prevailing strategies in cardiac surgery. In this study, the cutting‐edge bone adhesive is designed, inspired by the impressive adhesive properties found in mussels and sandcastle worms. We have created an osteogenic nanocomposite coacervate adhesive by integrating a cellulose‐polyphosphodopamide interpenetrating network, quaternized chitosan, and zinc, gallium‐doped hydroxyapatite nanoparticles. This adhesive is characterized by robust catechol–metal coordination… Show more
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