Engineering polyethersulfone hollow fiber membrane with improved blood compatibility and antibacterial property

Shi, Zhenqiang; Ji, Haifeng; Yu, Haichao; Huang, Xuelian; Zhao, Weifeng; Sun, Shudong; Zhao, Changsheng

doi:10.1007/s00396-015-3801-7

Cited by 33 publications

(13 citation statements)

References 50 publications

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“…Consequently, silver ions that cannot exhibit antibacterial properties are difficult to reduce to silver. Therefore, the choice of reduction method from among the chemical, physical, and biochemical methods, becomes important [8,9]. Chemical reduction is the most commonly-used method for preparing silver nanoparticles (AgNPs).…”

Section: Introductionmentioning

confidence: 99%

Thermosensitive Behavior and Super-Antibacterial Properties of Cotton Fabrics Modified with a Sercin-NIPAAm-AgNPs Interpenetrating Polymer Network Hydrogel

et al. 2018

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Poly(N-isopropylacrylamide) (PNIPAAm), sericin (SS), and silver nitrate were combined to prepare an interpenetrating network (IPN) hydrogel having dual functions of temperature sensitivity and antibacterial properties. The structure and size of AgNPs in such an IPN hydrogel were characterized by the Fourier Transform Infrared spectrum (FT-IR), X-ray powder diffraction (XRD) and Transmission Electron Microscope (TEM), and the thermal properties of the IPN hydrogel were characterized by Differential Scanning Calorimetry (DSC). Based on XRD patterns, Ag+ was successfully reduced to Ag0 by SS. It was observed by TEM that the particle size of silver particles was lower than 100 nm. The glass transition temperature (Tg) of IPN hydrogel was better than that of the PNIPAAm/AgNPs hydrogels, and lower critical solution temperature (LCST) values of the IPN hydrogel were obtained by DSC i.e. 31 °C. The thermal stability of the IPN hydrogel was successfully determined by the TGA. This IPN hydrogel was then used to modify the cotton fabrics by the “impregnation” method using glutaraldehyde (GA) as the cross-linking agent. The structures and properties of IPN hydrogel modified cotton fabric were characterized by scanning electron microscopy (SEM), FT-IR, and the thermogravimetry analysis (TGA). The results show that NIPAAm was successfully polymerized into PNIPAAm, and that there were neglected new groups in the hydrogel IPN. The IPN hydrogel was then successfully grafted onto cotton fabrics. SEM observations showed that the IPN hydrogel formed a membrane structure between the fibers, and improved the compactness of the fibers. At the temperature close to LCST (≈31 °C), the entire system was easily able to absorb water molecules. However, the hydrophilicity tended to decrease when the temperature was higher or lower than the LCST. The antibacterial rates of the modified cotton fabric against S. aureus and E. coli were as high as 99%.

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Section: Introductionmentioning

confidence: 99%

Thermosensitive Behavior and Super-Antibacterial Properties of Cotton Fabrics Modified with a Sercin-NIPAAm-AgNPs Interpenetrating Polymer Network Hydrogel

et al. 2018

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“…Polyethersulfone (PES) has been investigated intensely in the literature for preparing ultrafiltration membranes owing to its excellent properties which include (i) low protein adsorption; (ii) an ability to withstand exposure to high temperatures in water for prolonged periods, and a wide pH tolerances from pH 2 to 13; (iii) a superior ability to be functionalized with a wide range of molecules and polymers; (iv) an ability to form a membrane with reproducible properties and controllable pore size in a wide variety of configurations and modules; and (v) and a high degree of chemical and thermal stability due to its phenyl ether and phenyl sulfone group's availability . Despite its outstanding physical and chemical properties, PES has one serious limitation related to its intrinsic hydrophobic nature, which precludes the use of PES membranes to some extent in aqueous liquid filtration applications due to membrane fouling.…”

Section: Introductionmentioning

confidence: 99%

Graphene oxide, an effective nanoadditive for a development of hollow fiber nanocomposite membrane with antifouling properties

et al. 2018

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A series of hollow fiber (HF) membranes made from nanocomposites of polyethersulfone (PES) and graphene oxide (GO) at GO concentrations of 0.2%, 0.5%, and 1.0% were prepared by the dry-wet spinning process. The structure and the properties of as-prepared HF membranes were characterized by scanning electron microscopy (SEM); atomic force microscopy (AFM); measurements of contact angle, zeta potential, molecular weight cut-off (MWCO), and porosity; thermogravimetric analysis (TGA); and tensile testing. Long-term filtration tests were performed with the proteins bovine serum albumin (BSA), pepsin, trypsin, and lysozyme, which are common model organic foulants used in membrane fouling studies. The results showed that HF membrane made from PES/GO nanocomposite dope had a water permeability of 30 ± 1.5 Lm −2 hr −1 bar −1 , which is an increase of approximately 36% compared to that of a PES HF membrane. Among the membranes containing GO, the membrane with a 0.5 wt% GO loading exhibited the best antifouling performance, that is, this membrane recovered more than approximately 96% of its initial pure water flux, demonstrating a high resistance to the irreversible fouling. In addition, the same membrane showed an improvement in MWCO, an approximately 15% increase in porosity, along with optimum mechanical and thermal properties. K E Y W O R D Santifouling property, graphene oxide, hollow fiber membrane, nanocomposite

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“…As an engineering plastic, PES exhibits excellent mechanical properties, and the addition of other polymer components may significantly decrease its mechanical strength. 50 In this study, after the introduction of GO nanosheets, the GO-SPHF dual-layered membranes exhibited increased tensile strain and strength compared to PES/ SPHF1. This phenomenon could be attributed to the good mechanical properties of GO nanosheets.…”

Section: Mechanical Properties Of the Prepared Membrane Samplesmentioning

confidence: 61%

Graphene oxide and sulfonated polyanion co-doped hydrogel films for dual-layered membranes with superior hemocompatibility and antibacterial activity

Shi

Cheng

et al. 2016

Biomater. Sci.

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In this study, a new kind of hemocompatible and antibacterial dual-layered polymeric membrane was fabricated by coating a top layer of graphene oxide and a sulfonated polyanion co-doped hydrogel thin film (GO-SPHF) on a bottom membrane substrate. After a two-step spin-coating of casting solutions on glass plates, dual-layered membranes were obtained by a liquid-liquid phase inversion method. The GO-SPHF composite polyethersulfone (PES) membranes (PES/GO-SPHF) showed top layers with obviously large porous structures. The chemical composition tests indicated that there were abundant hydrophilic groups enriched on the membrane surface. The examination of membrane mechanical properties indicated that the composite membranes exhibited only slightly decreased performance compared to pristine PES membranes. Moreover, to validate the potential applications of this novel dual-layered membrane in diverse fields, we tested the hemocompatibility and antibacterial activity of the membranes, respectively. Notably, the PES/GO-SPHF membranes showed highly improved in vitro hemocompatibility, such as good anti-coagulant activity, suppressed platelet adhesion and activation, low inflammation potential, and good red blood cell compatibility. Furthermore, the dual-layered membranes exhibited robust antibacterial ability after in situ loading of Ag-nanoparticles with excellent bactericidal capability to both Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Due to the integration of the porous membrane structure, good mechanical strength, excellent hemocompatibility, as well as robust bactericidal capability, the GO and sulfonated polyanion co-doped dual-layered membranes may open up a new protocol to greatly demonstrate the potential application of polymeric membranes for clinical hemodialysis and many other biomedical therapies.

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Engineering polyethersulfone hollow fiber membrane with improved blood compatibility and antibacterial property

Cited by 33 publications

References 50 publications

Thermosensitive Behavior and Super-Antibacterial Properties of Cotton Fabrics Modified with a Sercin-NIPAAm-AgNPs Interpenetrating Polymer Network Hydrogel

Thermosensitive Behavior and Super-Antibacterial Properties of Cotton Fabrics Modified with a Sercin-NIPAAm-AgNPs Interpenetrating Polymer Network Hydrogel

Graphene oxide, an effective nanoadditive for a development of hollow fiber nanocomposite membrane with antifouling properties

Graphene oxide and sulfonated polyanion co-doped hydrogel films for dual-layered membranes with superior hemocompatibility and antibacterial activity

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