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<p>Iterative P450 enzymes are powerful biocatalysts for selective late-stage C-H oxidation of
complex natural product scaffolds. These enzymes represent new tools for selectivity and
cascade reactions, facilitating direct access to core structure diversification. Recently, we
reported the structure of the multifunctional bacterial P450 TamI and elucidated the molecular
basis of its substrate binding and strict reaction sequence at distinct carbon atoms of t… Show more
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