Engineering nanoprobes for magnetic resonance imaging of brain diseases

Zhang, Jingyi; Yu, Luodan; Yu, Meihua; Yu, Dehong; Chen, Yu; Zhang, Jun

doi:10.1016/j.cej.2023.148472

Cited by 1 publication

(1 citation statement)

References 161 publications

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“…The introduction of Fe NPs has completely transformed the MRI process, by enabling these NPs to be highly effective as contrast agents [217,224]. Nanosystems are thus able to remarkably tailor the relaxation times of distant water protons, which in turn facilitates the delineation of healthy and affected tissues with more precision [225]. The acidic microenvironment may break down the nanosystem to facilitate Fe 3 O 4 -PLGA-Ce6 liberation of Ce6 and iron ions.…”

Section: Fe Nps In Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%

Advances in the Optimization of Fe Nanoparticles: Unlocking Antifungal Properties for Biomedical Applications

Sandhu,

Raza,

Alqurashi

et al. 2024

Pharmaceutics

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In recent years, nanotechnology has achieved a remarkable status in shaping the future of biological applications, especially in combating fungal diseases. Owing to excellence in nanotechnology, iron nanoparticles (Fe NPs) have gained enormous attention in recent years. In this review, we have provided a comprehensive overview of Fe NPs covering key synthesis approaches and underlying working principles, the factors that influence their properties, essential characterization techniques, and the optimization of their antifungal potential. In addition, the diverse kinds of Fe NP delivery platforms that command highly effective release, with fewer toxic effects on patients, are of great significance in the medical field. The issues of biocompatibility, toxicity profiles, and applications of optimized Fe NPs in the field of biomedicine have also been described because these are the most significant factors determining their inclusion in clinical use. Besides this, the difficulties and regulations that exist in the transition from laboratory to experimental clinical studies (toxicity, specific standards, and safety concerns) of Fe NPs-based antifungal agents have been also summarized.

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Section: Fe Nps In Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%