Engineering H₂O₂ and O₂ Self‐Supplying Nanoreactor to Conduct Synergistic Chemiexcited Photodynamic and Calcium‐Overloaded Therapy in Orthotopic Hepatic Tumors (Adv. Healthcare Mater. 20/2022)

Abstract

Photodynamic Therapies In article 2201613 by Chia‐Hao Su, Chen‐Sheng Yeh, and co‐workers, the concept of self‐supplying H2O2 and O2 is presented by an all‐in‐one nanoreactor to process H2O2 and O2 generation, chemiluminescence resonance energy transfer (CRET) activated by the generated H2O2, and energy‐transfer to excite photosensitizer resulting in singlet oxygen formation. This allows the conduction of an external light‐fee CRET‐mediated photodynamic therapy, ushering in a new era in light‐based therapeutic interventions.