Engineering global and local signal generators for probing temporal and spatial cellular signaling dynamics
Haowen Yang,
Jurjen Tel
Abstract:Cells constantly encounter a wide range of environmental signals and rely on their signaling pathways to initiate reliable responses. Understanding the underlying signaling mechanisms and cellular behaviors requires signal generators capable of providing diverse input signals to deliver to cell systems. Current research efforts are primarily focused on exploring cellular responses to global or local signals, which enable us to understand cellular signaling and behavior in distinct dimensions. This review prese… Show more
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