Engineering and implementation of the new diffractometer – D3 – for the macromolecular crystallography beamlines of the Swiss Light Source

Maag, Stephan; Frommherz, U.; Kotrle, Goran; Thominet, Vincent; Welte, J.; Pradervand, Claude; Thermer, R.; Schnorf, D; Ellenberger, U.; Fuchs, Martin R.

doi:10.1088/1742-6596/425/1/012009

Cited by 2 publications

(4 citation statements)

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“…PRIGo was installed at beamline X06DA (PXIII) at the Swiss Light Source in January 2012 and is now fully integrated into the new data acquisition user interface DA+ (E. Panepucci et al, unpublished). Its compact design and small space envelope at large angles (Maag et al, 2013) (Fig. 5) maximize the achievable angular range but self-shadowing on the detector and potential collisions with beamline devices such as the collimator or the beam stop still impose angular restrictions.…”

Section: Integration Of Prigo At Beamline X06da (Pxiii) At Slsmentioning

confidence: 99%

PRIGo: a new multi-axis goniometer for macromolecular crystallography

et al. 2015

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The Parallel Robotics Inspired Goniometer (PRIGo) is a novel compact and high-precision goniometer providing an alternative to (mini-)kappa, traditional three-circle goniometers and Eulerian cradles used for sample reorientation in macromolecular crystallography. Based on a combination of serial and parallel kinematics, PRIGo emulates an arc. It is mounted on an air-bearing stage for rotation around ! and consists of four linear positioners working synchronously to achieve x, y, z translations and rotation (0-90 ), followed by a ' stage (0-360 ) for rotation around the sample holder axis. Owing to the use of piezo linear positioners and active correction, PRIGo features spheres of confusion of <1 mm, < 7 mm and < 10 mm for !, and ', respectively, and is therefore very well suited for micro-crystallography. PRIGo enables optimal strategies for both native and experimental phasing crystallographic data collection. Herein, PRIGo hardware and software, its calibration, as well as applications in macromolecular crystallography are described.

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Section: Integration Of Prigo At Beamline X06da (Pxiii) At Slsmentioning

confidence: 99%

PRIGo: a new multi-axis goniometer for macromolecular crystallography

et al. 2015

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“…The design thus could be kept as modular as possible, to both vibrationally isolate components from each other as well as maintain a high degree of configurability. Some details of the PSI construction and engineering have been described by Maag et al (2013).…”

Section: Hardwarementioning

confidence: 99%

“…To ensure that the PRIGo multi-axis goniometer (Glettig et al, 2011) can be integrated into the diffractometer set-up without any further modifications of the diffractometer, extensive integration studies were carried out during the construction phase of the single-axis system (Maag et al, 2013). In these studies, potential collisions with the lamp, the microscope, the beam-shaping devices and the cryogenic system were investigated.…”

Section: Sample Environmentmentioning

confidence: 99%

“…Both the aperture and the collimator finger are connected to their positioners via a magnetic kinematic mount (Maag et al, 2013), to allow for a quick and reproducible change to alternative aperture assemblies and also as a protection against accidental touching by operators or users. Directly underneath the magnetic mount, the positioner unit has two flexor tilt stages for rotational adjustment around the axes perpendicular to the beam.…”

Section: Beam Shaping and Diagnosticsmentioning

confidence: 99%

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