Engineered spidroin-derived high-performance fibers for diverse applications

Qin, Dawen; Li, Jingjing; Li, Huanrong; Zhang, Hongjie; Liu, Kai

doi:10.1007/s12274-023-5849-x

Cited by 7 publications

(3 citation statements)

References 114 publications

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“…Silk is one of the most promising materials for high-performance nano-composites. Kiseleva et al [180] and Qin et al [181] reviewed the recent advance in hybrid spider silk with inorganic nanomaterials for diverse applications. Prakash et al [182] reported in detail on composites using regenerated silk fibroin loaded with natural additives.…”

Section: Animal and Mineral Fibers And Nanocompositesmentioning

confidence: 99%

Natural Fibers Composites: Origin, Importance, Consumption Pattern, and Challenges

Thapliyal,

Verma,

Sen

et al. 2023

J. Compos. Sci.

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This comprehensive review explores the multifaceted world of natural fiber applications within the domain of composite materials. Natural fibers are meticulously examined in detail, considering their diverse origins, which encompass plant-derived fibers (cellulose-based), animal-derived fibers (protein-based), and even mineral-derived variations. This review conducts a profound analysis, not only scrutinizing their chemical compositions, intricate structures, and inherent physical properties but also highlighting their wide-ranging applications across various industries. The investigation extends to composites utilizing mineral or polymer matrices, delving into their synergistic interplay and the resulting material properties. Furthermore, this review does not limit itself to the intrinsic attributes of natural fibers but ventures into the realm of innovative enhancements. The exploration encompasses the augmentation of composites through the integration of natural fibers, including the incorporation of nano-fillers, offering a compelling avenue for further research and technological development. In conclusion, this review synthesizes a comprehensive understanding of the pivotal role of natural fibers in the realm of composite materials. It brings together insights from their diverse origins, intrinsic properties, and practical applications across sectors. As the final curtain is drawn, the discourse transcends the present to outline the trajectories of future work in the dynamic arena of natural fiber composites, shedding light on emerging trends that promise to shape the course of scientific and industrial advancements.

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Section: Animal and Mineral Fibers And Nanocompositesmentioning

confidence: 99%

Natural Fibers Composites: Origin, Importance, Consumption Pattern, and Challenges

Thapliyal,

Verma,

Sen

et al. 2023

J. Compos. Sci.

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“…[9,10] Additionally, the stacking of polyalanine modules into β-sheets forms a microcrystalline structure, contributing to the strength and molecular scaffold of the fibers. [11] It is noteworthy that the non-repetitive modules of spidroin, especially the carboxy-terminal domain (CTD), play critical roles in promoting the formation of hierarchical structures and regulating the mechanical performance of spider silk. [12] On the other hand, the noncrystalline modules containing random coil structures, e.g.…”

Section: Introductionmentioning

confidence: 99%

“…The strength and flexibility of spider silk are commonly attributed to the abundance of glycine/proline modules in spidroin [9,10] . Additionally, the stacking of polyalanine modules into β‐sheets forms a microcrystalline structure, contributing to the strength and molecular scaffold of the fibers [11] . It is noteworthy that the non‐repetitive modules of spidroin, especially the carboxy‐terminal domain (CTD), play critical roles in promoting the formation of hierarchical structures and regulating the mechanical performance of spider silk [12] .…”

Section: Introductionmentioning

confidence: 99%

Spidroin‐mimetic Engineered Protein Fibers with High Toughness and Minimized Batch‐to‐batch Variations through β‐sheets Co‐assembly

Qin,

Wang,

Cheng

et al. 2024

Angewandte Chemie

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Synthetic spidroin fibers have not yet attained the same level of toughness and stability as natural spider silks due to the complexity of composition and hierarchical structure. Particularly, understanding the intricate interactions between spidroin components in spider fiber is still elusive. Herein, we report modular design and preparation of spidroin‐mimetic fibers composed of a conservative C‐terminus spidroin module, two different natural β‐sheets modules, and a non‐spidroin random‐coil module. The resulting fibers exhibit a toughness of ~200 MJ/m3, reaching the highest value among the reported artificial spider silks. The interactions between two components of recombinant spidroins facilitate the intermolecular co‐assembly of β‐sheets, thereby enhancing the mechanical strength and reducing batch‐to‐batch variability in the dual‐component spidroin fibers. Additionally, the dual‐component spidroin fibers offer potential applications in implantable or even edible devices. Therefore, our work presents a generic strategy to develop high‐performance protein fibers for diverse translations in different scenarios.

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Modular Protein Fibers with Outstanding High‐Strength and Acid‐Resistance Performance Mediated by Copper Ion Binding and Imine Networking

Wang,

Yang,

Jia

et al. 2024

Advanced Materials

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Engineered protein fibers are promising biomaterials with diverse applications due to their tunable protein structure and outstanding mechanical properties. However, it remains challenging at the molecular level to achieve satisfied mechanical properties and environmental tolerance simultaneously, especially under extreme acid conditions. Herein, we report the construction of artificial fibers comprising chimeric proteins made of rigid amyloid peptide and flexible cationic elastin‐like protein modules. The amyloid peptide readily assembles into highly organized β‐sheet structures that can be further strengthened by the coordination of Cu2+, while the flexible cation elastin‐like protein module allows the formation of imine‐based crosslinking networks. These double networks synergistically enhance the mechanical properties of the fibers, leading to a high tensile strength and toughness, overwhelming many reported recombinant spidroin fibers. Notably, the coordination of Cu2+ with serine residues could stabilize β‐sheet structures in the fibers under acidic conditions, which makes the fibers robust against acid, thus enabling their successful utilization in gastric perforation suturing. Our work highlights the customization of double networks at the molecular level to create tailored high‐performance protein fibers for various application scenarios.This article is protected by copyright. All rights reserved

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Engineered spidroin-derived high-performance fibers for diverse applications

Cited by 7 publications

References 114 publications

Natural Fibers Composites: Origin, Importance, Consumption Pattern, and Challenges

Natural Fibers Composites: Origin, Importance, Consumption Pattern, and Challenges

Spidroin‐mimetic Engineered Protein Fibers with High Toughness and Minimized Batch‐to‐batch Variations through β‐sheets Co‐assembly

Modular Protein Fibers with Outstanding High‐Strength and Acid‐Resistance Performance Mediated by Copper Ion Binding and Imine Networking

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