Abstract:Periprosthetic osteolysis induced by the ultrahighmolecular-weight polyethylene (UHMWPE) wear particles is a major complication associated with the sustained service of artificial joint prostheses and often necessitates revision surgery. Therefore, a smart implant with direct prevention and repair abilities is urgently developed to avoid painful revision surgery. Herein, we fabricate a phosphatidylserine-and polyethylenimine-engineered niobium carbide (Nb 2 C) MXenzyme-coated micro/nanostructured titanium impl… Show more
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