“…Unlike invasive carriers, drug delivery of smart nano-carriers is based on the external stimuli like magnetic field or ultrasound ( Jindal and Gopinath, 2020 ). Likewise the effective demonstration of nano-carriers in the treatment of Human Immunodeficiency Virus (HIV), Hepatitis, Influenza A virus etc., ( Abd Elkodous et al, 2019 ; Negahdari et al, 2019 ; Kim et al, 2020 ), the existing drugs are being tested for the treatment of SARS-CoV-2 infection. Since SARS-CoV-2 infects the respiratory system, the drugs are administered through non-invasive methods.…”
Section: Present Status and Future Perspectivesmentioning
Coronavirus disease (COVID-19) has emerged as a fast-paced epidemic in late 2019 which is disrupting life-saving immunization services. SARS-CoV-2 is a highly transmissible virus and an infectious disease that has caused fear among people across the world. The worldwide emergence and rapid expansion of SARS-CoV-2 emphasizes the need for exploring innovative therapeutic approaches to combat SARS-CoV-2. The efficacy of some antiviral drugs such as remdesivir, favipiravir, umifenovir, etc., are still tested against SARS-CoV-2. Additionally, there is a large global effort to develop vaccines for the protection against COVID-19. Because vaccines seem the best solution to control the pandemic but time is required for its development, pre-clinical/clinical trials, approval from FDA and scale-up. The nano-based approach is another promising approach to combat COVID-19 owing to unique physicochemical properties of nanomaterials. Peptide based vaccines emerged as promising vaccine candidates for SARS-CoV-2. The study emphasizes the current therapeutic approaches against SARS-CoV-2 and some of the potential candidates for SARS-CoV-2 treatment which are still under clinical studies for their effectiveness against SARS-CoV-2. Overall, it is of high importance to mention that clinical trials are necessary for confirming promising drug candidates and effective vaccines and the safety profile of the new components must be evaluated before translation of in vitro studies for implementation in clinical use.
“…Unlike invasive carriers, drug delivery of smart nano-carriers is based on the external stimuli like magnetic field or ultrasound ( Jindal and Gopinath, 2020 ). Likewise the effective demonstration of nano-carriers in the treatment of Human Immunodeficiency Virus (HIV), Hepatitis, Influenza A virus etc., ( Abd Elkodous et al, 2019 ; Negahdari et al, 2019 ; Kim et al, 2020 ), the existing drugs are being tested for the treatment of SARS-CoV-2 infection. Since SARS-CoV-2 infects the respiratory system, the drugs are administered through non-invasive methods.…”
Section: Present Status and Future Perspectivesmentioning
Coronavirus disease (COVID-19) has emerged as a fast-paced epidemic in late 2019 which is disrupting life-saving immunization services. SARS-CoV-2 is a highly transmissible virus and an infectious disease that has caused fear among people across the world. The worldwide emergence and rapid expansion of SARS-CoV-2 emphasizes the need for exploring innovative therapeutic approaches to combat SARS-CoV-2. The efficacy of some antiviral drugs such as remdesivir, favipiravir, umifenovir, etc., are still tested against SARS-CoV-2. Additionally, there is a large global effort to develop vaccines for the protection against COVID-19. Because vaccines seem the best solution to control the pandemic but time is required for its development, pre-clinical/clinical trials, approval from FDA and scale-up. The nano-based approach is another promising approach to combat COVID-19 owing to unique physicochemical properties of nanomaterials. Peptide based vaccines emerged as promising vaccine candidates for SARS-CoV-2. The study emphasizes the current therapeutic approaches against SARS-CoV-2 and some of the potential candidates for SARS-CoV-2 treatment which are still under clinical studies for their effectiveness against SARS-CoV-2. Overall, it is of high importance to mention that clinical trials are necessary for confirming promising drug candidates and effective vaccines and the safety profile of the new components must be evaluated before translation of in vitro studies for implementation in clinical use.
“…16 Nanomaterials possess relatively higher degrees of chemical, physical and biological activities due to their large surface area with respect to their bulk counterparts. [17][18][19][20][21] Among nanomaterials, titanium dioxide (TiO 2 ) is still a very promising candidate for light-assisted photocatalysis and degradation of many kinds of pollutant present in wastewater. 22 TiO 2 nanoparticles (NPs) are chemically active, abundant, non-toxic and possess satisfactory photocatalytic activity.…”
In this paper, we report a layer-by-layer approach for the preparation of a concentric recyclable composite (CoxNi1−xFe2O4/SiO2/TiO2; x = 0.9) designed for wastewater treatment.
“…Many types of NMs showed very promising antiviral and antimicrobial activities which could be used as nano-vaccines to prevent microbial biofilm formation and the adsorption of microbes onto the surfaces and to control their transmission as shown in Fig. 1 (Abd Elkodous et al 2019a , b ; 2020 ; Chen and Liang 2020 ; El-Sayyad et al 2020 ; Kim et al 2020 ; Mohamed et al 2020 ; Tran et al 2020 ; Wong et al 2020 ). Fig.…”
Section: Nanomaterials As Promising Nano-vaccines and Nano-drugmentioning
In this editorial trend, we aim to collect and present recently available data about the characteristics of SARS-CoV-2 virus, severity, infection, replication, diagnosis, and current medications. In addition, we propose the role of nanomaterials in controlling and treating COVID-19 through their antiviral and antibacterial potential with suggested action mechanisms indicating the capability of interaction between these nanomaterials and SARS-CoV-2. These nanomaterials might be among the possible and most effective cures against coronavirus.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
