Engagement of scientists with the public and policymakers to promote alternative methods

Aulock, Sonja von; Busquet, François; Locke, Paul A.; Herrmann, Kathrin; Hartung, Thomas

doi:10.14573/altex.2209261

Cited by 8 publications

(4 citation statements)

References 36 publications

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“…Non-governmental organizations (NGO) play a major role in influencing policy-making (von Aulock et al, 2022) relevant to alternative approaches. Animal experimentation is a contentious issue between environmental NGOs and animal welfare NGOs due to their differing perspectives on its implications.…”

Section: Opposing Views Of Environmental and Animal Welfare Ngos On A...mentioning

confidence: 99%

Alternative methods go green! Green toxicology as a sustainable approach for assessing chemical safety and designing safer chemicals

2024

ALTEX

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Green toxicology is marching chemistry into the 21 st century. This emerging framework will transform how chemical safety is evaluated by incorporating evaluation of the hazards, exposures, and risks associated with chemicals into early product development in a way that minimizes adverse impacts on human and environmental health. The goal is to minimize toxic threats across entire supply chains through smarter designs and policies. Traditional animal testing methods are replaced by faster, cutting-edge innovations like organs-on-chips and artificial intelligence predictive models that are also more cost-effective. Core principles of green toxicology include utilizing alternative test methods, applying the precautionary principle, considering lifetime impacts, and emphasizing risk prevention over reaction. This paper provides an overview of these foundational concepts and describes current initiatives and future opportunities to advance the adoption of green toxicology approaches. Challenges and limitations are also discussed. Green shoots are emerging with governments offering carrots like the European Green Deal to nudge industry. Noteworthy, animal rights and environmental groups have different ideas about the needs for testing and their consequences for animal use. Green toxicology represents the way forward to support both these societal needs with sufficient throughput and human relevance for hazard information and minimal animal suffering. Green toxicology thus sets the stage to synergize human health and ecological values. Overall, the integration of green chemistry and toxicology has potential to profoundly shift how chemical risks are evaluated and managed to achieve safety goals in a more ethical, ecologically-conscious manner.

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Section: Opposing Views Of Environmental and Animal Welfare Ngos On A...mentioning

confidence: 99%

Alternative methods go green! Green toxicology as a sustainable approach for assessing chemical safety and designing safer chemicals

2024

ALTEX

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“…These considerations should also be applied in the review of scientific articles. Championing new approach methodologies encompasses engaging with different interest groups on this subject and developing tailored communication skills to form community and grow a wider understanding and support of these methodologies and their implementation (von Aulock et al, 2022). , A., Groff, K., Stuck, A. O. et al (2022).…”

Section: Meeting Reportmentioning

confidence: 99%

Alternative Methods in Science: Towards Fluidic Systems

Caloni

2023

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“…The Einstein Center 3R ( EC3R ) is a network of all relevant biomedical research institutions in Berlin. 9,10 The centre is headed by its spokesperson, Prof. Hippenstiel, and co-spokespersons, Prof. Thöne-Reineke and Prof. Kurreck. The activities of EC3R are supervised by a steering committee and an international scientific board.…”

Section: Organisational Structures Of Three Rs Centres and Platformsmentioning

confidence: 99%

The Current Status and Work of Three Rs Centres and Platforms in Europe*

et al. 2022

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The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes has given a major push to the formation of Three Rs initiatives in the form of centres and platforms. These centres and platforms are dedicated to the so-called Three Rs, which are the Replacement, Reduction and Refinement of animal use in experiments. ATLA’s 50th Anniversary year has seen the publication of two articles on European Three Rs centres and platforms. The first of these was about the progressive rise in their numbers and about their founding history; this second part focuses on their current status and activities. This article takes a closer look at their financial and organisational structures, describes their Three Rs focus and core activities (dissemination, education, implementation, scientific quality/translatability, ethics), and presents their areas of responsibility and projects in detail. This overview of the work and diverse structures of the Three Rs centres and platforms is not only intended to bring them closer to the reader, but also to provide role models and show examples of how such Three Rs centres and platforms could be made sustainable. The Three Rs centres and platforms are very important focal points and play an immense role as facilitators of Directive 2010/63/EU ‘on the ground’ in their respective countries. They are also invaluable for the wide dissemination of information and for promoting the implementation of the Three Rs in general.

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Engagement of scientists with the public and policymakers to promote alternative methods

Cited by 8 publications

References 36 publications

Alternative methods go green! Green toxicology as a sustainable approach for assessing chemical safety and designing safer chemicals

Alternative methods go green! Green toxicology as a sustainable approach for assessing chemical safety and designing safer chemicals

Alternative Methods in Science: Towards Fluidic Systems

The Current Status and Work of Three Rs Centres and Platforms in Europe*

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