Enfermedad relacionada a IgG4: Manifestaciones extrapancreáticas en pancreatitis autoinmune

Berger, Zoltán; A, Carla Mancilla

doi:10.4067/s0034-98872014001000019

Rev. méd. Chile

2014

DOI: 10.4067/s0034-98872014001000019

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Enfermedad relacionada a IgG4: Manifestaciones extrapancreáticas en pancreatitis autoinmune

Zoltán Berger

Carla Mancilla A

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Imaging findings of IgG4-related kidney disease without extrarenal organ involvement

Zhang

Yang²

2019

Medicine

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Rationale: IgG4-related disease (IgG4-RD) is a systemic chronic inflammatory disorder that can affect almost every organ. IgG4-RD includes IgG4-related kidney disease (IgG4-RKD), but lesions affecting the kidney alone or first are very rare, and a complete understanding is lacking. Computed tomography (CT) and magnetic resonance imaging (MRI) findings can show the typical characteristics of IgG4-RKD and provide information for accurate and rapid diagnosis. Patient concerns: We report a case of a 60-year-old woman who was admitted to our hospital for dizziness and instability while walking, her bilateral eyelids were also slightly swollen. She had no medical history. Diagnoses: CT and MRI images of the patient revealed multiple local and diffuse patchy lesions in the bilateral renal parenchyma and mass-like tissue in the bilateral renal pelvis, accompanied by right hydronephrosis. A pathological examination of renal samples showed numerous lymphocyte and plasma cell infiltration. Immunohistochemistry demonstrated approximately 50% of the IgG-positive plasma cells to be IgG4+. The serum IgG level was obviously elevated, with both C3and C4 levels were reduced. The patient was diagnosed with IgG4-RKD. Interventions: The patient received corticosteroid therapy at another hospital. Outcomes: The bilateral kidney lesions were smaller on follow-up CT images. Lessons: IgG4-RKD exhibits some characteristic imaging features. Despite the relatively low incidence of IgG4-RKD, it should be included in differential diagnoses when images show multiple lesions in kidneys with mild and delayed enhancement and hypointensity on T2WI in middle-aged to elderly patients

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Imaging findings of IgG4-related kidney disease without extrarenal organ involvement

Zhang

Yang²

2019

Medicine

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Oil Concession Contracts and the Problem of Hold-Up

Brinsmead¹

2007

SSRN Journal

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Enfermedad relacionada a IgG4: Manifestaciones extrapancreáticas en pancreatitis autoinmune

Cited by 2 publications

References 4 publications

Imaging findings of IgG4-related kidney disease without extrarenal organ involvement

Imaging findings of IgG4-related kidney disease without extrarenal organ involvement

Oil Concession Contracts and the Problem of Hold-Up

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