Enfermedad de Chagas crónica.Ausencia de Triatoma infestans intradomiciliario y persistencia de Trypanosoma cruzi circulante post-terapia

Zulantay, Inés; Bozán, Francisca; Salas, Carlos; Zilleruelo, Nicolás; Osuna, Antonio; Gil, Luis Carlos; Rodríguez, Jorge; Rojas, Antonio; Egea, Jose L.; Apt, Werner

doi:10.4067/s0717-77122004000300001

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…In the literature, intradomicile building materials are widely recognized as influential factors in the spread of CD. Structures built with precarious materials create a conducive environment for insects, providing shelter and facilitating their proliferation [27,52,61,65,[85][86][87][88][89][90][91][92][93][94][95]. The research also found infected individuals living in well-structured homes, but who had previously lived in households with precarious conditions, like Chagasinfected pregnant women from Pore, Casanare, Colombia [31].…”

Section: ➢ Intradomicile Buildingmentioning

confidence: 98%

“…In studies where no search for triatomines was conducted in the houses of infected individuals, but rather only questioning about the presence of these insects in the households [89,95], the influence of the kissing bug in the domestic environment has been observed. This is supported by the identification of a two-fold increase in the odds of T. cruzi infection among young people aged between 10 and 20 years, confirming the presence of vectors in their households, in rural communities in Argentina (OR = 2.08) [110].…”

Section: ➢ Triatomines In the Householdsmentioning

confidence: 99%

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Predictor Variables in the Spread of Chagas Disease in Rural Areas

de Sousa Leite,

de Rezende Feres,

Scalize

2024

Pathogens

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Over a hundred years ago after the discovery of Chagas disease (CD) in Brazil, the World Health Organization estimates a number of 6 to 7 million people infected by Trypanosoma cruzi worldwide. Therefore, the goal of this work was to identify variables related to the spread of infection by T. cruzi in humans living in rural areas, seeking predictor variables. A systematic review of the literature has been conducted, with a search in the Scopus platform, using the search string “Chagas disease” and “rural”, resulting in 85 valid and analyzed scientific studies (1977 and 2022). Twenty-seven predictor variables have been acquired, and 19 of them have been grouped, such as: socioeconomic and educational, housing, environmental, sanitary, and cultural; and 8 variables related to T. cruzi seropositive individuals. The predictor variables yielded significant results (p-value < 0.05) in 59.5% of the cases (195/328), with a median of 66.7%. In other words, studies relating to 50% of the 27 variables showed significance equal to or greater than 66.7% of the time. The independent variables with the highest proportion of significant data (p-value < 0.05) were Education (87.6%), Intradomicile building (70%), Domestic animals (69.6%), and Triatomines (69.2%) in the households. Some variables reached 100%; however, few articles were found, indicating the need for further research, especially for Sanitation and Culture. It has been concluded that, in the several contexts found, the social vulnerability and lack of information led the individual to living in environments where inhabitability is inadequate, to perform limited work activity and develop habits and behaviors which impair them in an environmental insalubrity situation, favorable to the access of vectors and pathogens of anthropozoonoses such as CD.

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Section: ➢ Intradomicile Buildingmentioning

confidence: 98%

Section: ➢ Triatomines In the Householdsmentioning

confidence: 99%

Predictor Variables in the Spread of Chagas Disease in Rural Areas

de Sousa Leite,

de Rezende Feres,

Scalize

2024

Pathogens

View full text Add to dashboard Cite

show abstract

“…Pacientes: Treinta pacientes chagásicos crónicos, con reacciones de ELISA e inmunofluorescencia indirecta positivas para enfermedad de Chagas, 16 hombres y 14 mujeres, con edad promedio 33,2 años (rango 10 a 50), procedentes de áreas de la IV región, bajo control anti-Triatoma infestans 15 , formaron parte de un ensayo clínico randomizado que evaluó eficacia y tolerancia de ITRA y ALO 16 . Se agruparon de acuerdo a la positividad (Grupo I) o negatividad (Grupo II) de tres pruebas parasitológi-cas (XD, PCR e HIB), aplicados en un período promedio de 84,1 meses post-terapia.…”

Section: Materials Y Métodounclassified