Since the last few decades the world has been facing global warming due to the increased percentage of atmospheric CO2. Much attention is therefore devoted to building air conditioning and, mechanical ventilation (ACMV) systems to provide a comfortable environment to occupants of residential houses and buildings. Liquid Desiccant Dehumidification System (LDDS) has gained much attention due to the possibility of combining secondary level energy sources like renewable energy and waste heat as its main energy source. However, the regeneration process of LDDS absorbs a vast amount of heat to vaporize water from the weak desiccant solution. With proper study and investigation nevertheless, challenges such as the requirement of high temperature heat sources, inefficiency of the regeneration process, and the complexity of combining renewable energy sources with the regeneration system can be overcome.