Energy Migration Control of Multimodal Emissions in an Er³⁺‐Doped Nanostructure for Information Encryption and Deep‐Learning Decoding

Abstract

Modulating the emission wavelengths of materials has always been a primary focus of fluorescence technology. Nanocrystals (NCs) doped with lanthanide ions with rich energy levels can produce a variety of emissions at different excitation wavelengths. However, the control of multimodal emissions of these ions has remained a challenge. Herein, we present a new composition of Er3+‐based lanthanide NCs with color‐switchable output under irradiation with 980, 808, or 1535 nm light for information security. The variation of excitation wavelengths changes the intensity ratio of visible (Vis)/near‐infrared (NIR‐II) emissions. Taking advantage of the Vis/NIR‐II multimodal emissions of NCs and deep learning, we successfully demonstrated the storage and decoding of visible light information in pork tissue.

Cyanine‐Doped Lanthanide Metal–Organic Frameworks for Near‐Infrared II Bioimaging

“…Near‐infrared II (NIR‐II, 1000–1700 nm) imaging, especially in the NIR‐IIb (1500–1700 nm) region, has evoked increasing attention in the recent years due to its significantly higher penetration and resolution originating from the notably decreased scattering and absorption in this region. [ 5 ] Therefore, it is of great significance to develop MOFs with strong NIR‐II emission and hence suitable for use in vivo. Rational design of ligands is an effective way to gain redshift of the emission wavelength.…”

Targeted Immunoimaging of Tumor‐Associated Macrophages in Orthotopic Glioblastoma by the NIR‐IIb Nanoprobes

“…[40][41][42] Previous studies have demon strated that lanthanide-doped nanoparticles show great potential in bioimaging because of their tunable multiple excitations and emissions, excellent photostability, and biocompatibility. [43][44][45] Specially, Er-based nanoparticles can be excited by 808 nm or 980 nm laser to emit 1525 nm down-shifting fluorescence, which makes them very attractive in orthotopic GBM imaging due to their deep penetration. [43,46] However, the excitation wavelength (i.e., 980 nm) coincidentally locates in the strong absorption window of water, which can trigger severe aqueous quenching effect on their fluorescence in vitro and produce local overheating to damage cells and tissues in vivo under continuous laser excitation.…”

“…[43][44][45] Specially, Er-based nanoparticles can be excited by 808 nm or 980 nm laser to emit 1525 nm down-shifting fluorescence, which makes them very attractive in orthotopic GBM imaging due to their deep penetration. [43,46] However, the excitation wavelength (i.e., 980 nm) coincidentally locates in the strong absorption window of water, which can trigger severe aqueous quenching effect on their fluorescence in vitro and produce local overheating to damage cells and tissues in vivo under continuous laser excitation. [47] Therefore, it is of great importance to engineer the fluorescence of Er-based nanoparticles, which can ultimately realize targeted imaging of M2-type TAMs in orthotopic GBM under 980 nm laser irradiation with low power density.…”

Controlling the Energy‐Transfer Processes in a Nanosized Molecular Upconverter to Tap into Luminescence Thermometry Application

“…The phenomenon of photon upconversion (UC) continues to fascinate researchers from multiple disciplines due to their tremendous potential application in areas ranging from luminescent sensors and anti‐counterfeiting materials to biological imaging probes [1–22] . Since its discovery in 1966, [2] low‐phonon solids and nanoparticles (NPs) were extensively investigated with a high degree of success.…”