We use the AdS/CFT correspondence to determine the rate of energy loss of a heavy quark moving through N = 4 SU (N c ) supersymmetric Yang-Mills plasma at large 't Hooft coupling. Using the dual description of the quark as a classical string ending on a D7-brane, we use a complementary combination of analytic and numerical techniques to determine the friction coefficient as a function of quark mass. Provided strongly coupled N = 4 Yang-Mills plasma is a good model for hot, strongly coupled QCD, our results may be relevant for charm and bottom physics at RHIC.