Levulinic acid (LA) recently has attracted much attention as a promising biorefinery platform due to its potential to be economical and sustainable. This paper addresses technical, techno-economic, and exergetic analyses of an industrial LA production via acid-catalyzed dehydration. The process was simulated through Aspen Plus, considering a processing capacity of 15,175.60 kg/h of banana empty fruit bunches. The global productivity yield was 25.56%, producing 3883.13 kg/h of LA. The techno-economic analysis evidenced that this process may be an attractive alternative for biomass valorization, considering the obtained financial results. This process's total production cost was 0.178 $USD per kilogram of biomass and a total annualized cost of $USD 29,163,638.95. Exergy analysis revealed that this process had an irreversibility rate of 1.48 × 10 5 MJ/h. The pretreatment stage presented the lowest exergetic efficiency. Globally, the exergy efficiency was 53.76%, which is within the reported results for analogous biomass transformation processes.