Energy drink exposures reported to Texas poison centers: Analysis of adverse incidents in relation to total sales, 2010–2014

Borron, Stephen W.; Watts, Susan; Herrera, Jessica; Larson, Joshua H.; Baeza, Salvador Calzado; Kingston, Richard L.

doi:10.1016/j.yrtph.2018.05.008

Cited by 8 publications

(7 citation statements)

References 44 publications

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“…The seizures decreased again when he started to drink decaffeinated iced tea. There are also anecdotal reports of seizures after the intake of energy drinks [28]. Caffeine was also found to prolong seizures after electroconvulsive therapy, a treatment for severe depression [29].…”

Section: Case Reportsmentioning

confidence: 99%

The Use of Caffeine by People with Epilepsy: the Myths and the Evidence

Bauer

Sander

2019

Curr Neurol Neurosci Rep

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Purpose of review: Caffeine is the most widely consumed central nervous stimulant. For people with epilepsy, it is often unclear whether drinking coffee carries a risk of triggering seizures. Recent findings: The relationship between caffeine, seizures, epilepsy and anti-seizure drugs is not fully understood. Clinical studies are scarce. In animal models, caffeine can increase seizure susceptibility but can also protect from seizures. Effects seem dose-dependent and, influenced but the duration of intake and the developmental stage at which caffeine exposure started. Caffeine lowers the efficacy of several anti-seizure medication, especially topiramate. Summary: It is unclear how these findings, mainly from animal studies can be translated to the clinical condition. At present, there is no evidence to advice people with epilepsy against the use or overuse of caffeine. Until clinical studies suggest otherwise, caffeine intake should be considered as a factor in achieving and maintaining seizure control in epilepsy.

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Section: Case Reportsmentioning

confidence: 99%

The Use of Caffeine by People with Epilepsy: the Myths and the Evidence

Bauer

Sander

2019

Curr Neurol Neurosci Rep

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“…The primary search yielded 21 458 publications (PubMed, n = 4778; Scopus, n = 16 680). Only 50 studies met all the inclusion criteria and were included in the current systematic review 9–58 (Figure 1). One study was identified through the scanning of the reference lists of other reviews 41 …”

Section: Resultsmentioning

confidence: 99%

“…In total, 17 articles investigated various non‐alcoholic drinks in human studies of patients with epilepsy or healthy individuals (Table 1). 9–25 Briefly, these studies showed that kinnow juice 10 and grapefruit juice 11 may significantly raise the bioavailability of carbamazepine. In one study in healthy male volunteers, with kinnow juice, the peak serum concentration and area under the serum concentration‐time curve of carbamazepine was significantly increased and time to reach the peak serum concentration was significantly decreased as compared with water 10 .…”

Section: Resultsmentioning

confidence: 99%

Caffeinated drinks, fruit juices, and epilepsy: A systematic review

Asadi‐Pooya

Zeraatpisheh

Rostaminejad

et al. 2021

Acta Neuro Scandinavica

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The aim of this systematic review was to provide the required information regarding different aspects of the relationship between epilepsy/antiseizure medications and non‐alcoholic drinks. The recommendations of the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) statement were followed. MEDLINE and Scopus from the inception until 7 August 2021 were systematically searched. These key words were used: “epilepsy” OR “seizure” OR “antiepileptic” OR “antiseizure” OR “anticonvulsant” AND “coffee” OR “tea” OR “soda” OR “juice” OR “drink” OR “cola” OR “diet” (35 key word combinations). The primary search yielded 21 458 publications (PubMed, n = 4778; Scopus, n = 16 680). Only 50 studies met all the inclusion criteria and were included in the current systematic review. In total, 17 articles investigated various non‐alcoholic drinks in human studies, 11 studies were case reports/series, and 22 articles were animal/in vitro studies. None of the studies provided a class 1 of evidence. There is limited evidence suggesting that certain drinks (eg, caffeinated energy drinks) might trigger seizures. Patients with epilepsy should avoid excessive consumption of certain fruit juices (eg, grapefruit, lime, pomegranate, kinnow, and star fruit) and caffeinated drinks. However, daily coffee and tea intake can be part of a healthy balanced diet, and their consumption does not need to be stopped in patients with epilepsy. Coffee/tea consumption is not harmful if consumed at levels of 200 mg (caffeine) in one sitting (about 2½ cups of coffee) or 400 mg daily (about five cups of coffee).

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“…Several other international studies (Borron et al, 2018, Gunja and Brown, 2012, Markon et al, 2019, Seifert et al, 2013 provide analysis of adverse reactions related to CED exposures based on calls to poison information centers. A study based on the Texas poison center network (TPCN) reported data from single substance exposures to CED (multiple product types or CEDs in combination with other substances such as alcohol were excluded) from 2010 to 2014 (Borron et al, 2018). Over this 5-year period, 855 documented CED exposures were reported out of a total of 752 279 calls to the TPCN, or 0.11%.…”

Section: ) Poison Information Center Datamentioning

confidence: 99%

Caffeinated energy drinks in the Canadian context: health risk assessment with a focus on cardiovascular effects

Vieille

Gillespie

Bonvalot

et al. 2021

Appl. Physiol. Nutr. Metab.

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In Canada, Caffeinated Energy Drinks (CEDs) currently sold under Temporary Marketing Authorizations must meet strict eligibility criteria. These criteria, which include compositional and labelling requirements, were developed based on the outcome of a health risk assessment conducted by Health Canada (HC) in 2013. HC updated its assessment by reviewing new information with the focus on potential cardiovascular (CV) effects associated with the consumption of CEDs available for sale in Canada. Due to limited data on CED consumption among Canadians to derive accurate exposure information, the composition of a typical CED was characterized to assess the potential effects of single ingredients and synergistic interactions between ingredients, on the cardiovascular system. Surveillance data on potential adverse effects related to CED consumption was also analysed. After extensive review, HC’s updated assessment confirms the current risk management approach for CEDs is health protective for Canadian consumers, including the potential for cardiovascular effects. The available evidence supports that moderate consumption (up to 500 ml per day) of a typical CED authorized for sale in Canada is safe for the general population of healthy adults and adolescents. It also re-confirms vulnerable sub-populations (i.e., children, pregnant and/or breastfeeding women, and caffeine-sensitive individuals) should not consume CEDs. NOVELTY: • Consumption up to 500 ml per day of a typical CED is not associated with an increased risk of cardiovascular effects • Children, pregnant and/or breastfeeding women, and caffeine-sensitive individuals should not consume CEDs

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Energy drink exposures reported to Texas poison centers: Analysis of adverse incidents in relation to total sales, 2010–2014

Cited by 8 publications

References 44 publications

The Use of Caffeine by People with Epilepsy: the Myths and the Evidence

The Use of Caffeine by People with Epilepsy: the Myths and the Evidence

Caffeinated drinks, fruit juices, and epilepsy: A systematic review

Caffeinated energy drinks in the Canadian context: health risk assessment with a focus on cardiovascular effects

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