Energy dependence of the response of thermoluminescence dosimeters to photon and electron beams

Olivera, G.; Kessler, C; Sansogne, R; Saravi, M.

doi:10.1016/0168-583x(94)95707-x

Cited by 9 publications

(10 citation statements)

References 12 publications

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“…require specialized equipment, can be cumbersome to operate, exhibit energy dependence, can require expensive fabrication processes, do not conform to human anatomical features, and / or use sophisticated and expensive visualization modalities including magnetic resonance imaging (MRI). [6][7][8] In many cases, they may also fail to provide information about the delivered dose at more than one point in the patient and the dose may be reported with insufficient spatial resolution. A novel dosimeter that can overcome these limitations, while demonstrating robust performance, can result in safe and effective monitoring radiation doses in proton therapy, potentially leading to improved patient outcomes.…”

Section: 1overviewmentioning

confidence: 99%

Hydrogel Nanosensors for Colorimetric Detection and Dosimetry in Proton Beam Radiotherapy

Inamdar

Pushpavanam

Lentz

et al. 2018

ACS Appl. Mater. Interfaces

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Proton beam therapy (PBT) is a state-of-the-art radiotherapy treatment approach that uses focused proton beams for tumor ablation. A key advantage of this approach over conventional photon radiotherapy (XRT) is the unique dose deposition characteristic of protons, which results in superior healthy tissue sparing. This results in fewer unwanted side effects and improved outcomes for patients. Currently available dosimeters are intrinsic, complex, and expensive and are not routinely used to determine the dose delivered to the tumor. Here, we report a hydrogel-based plasmonic nanosensor for detecting clinical doses used in conventional and hyperfractionated proton beam radiotherapy. In this nanosensor, gold ions, encapsulated in a hydrogel, are reduced to gold nanoparticles following irradiation with proton beams. Formation of gold nanoparticles renders a color change to the originally colorless hydrogel. The intensity of the color can be used to calibrate the hydrogel nanosensor in order to quantify different radiation doses employed during proton treatment. The potential of this nanosensor for clinical translation was demonstrated using an anthropomorphic phantom mimicking a clinical radiotherapy session. The simplicity of fabrication, detection range in the fractionated radiotherapy regime, and ease of detection with translational potential makes this a first-in-kind plasmonic colorimetric nanosensor for applications in clinical proton beam therapy.

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Section: 1overviewmentioning

confidence: 99%

Hydrogel Nanosensors for Colorimetric Detection and Dosimetry in Proton Beam Radiotherapy

Inamdar

Pushpavanam

Lentz

et al. 2018

ACS Appl. Mater. Interfaces

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“…O'Brien (1977), Holt et al (1975) and Ogunleye and Paliwal (1985) proposed other general cavity theories for electron beams. The theoretical predictions of the energy response by the different electron cavity theories for LiF TLDs vary considerably (Olivera et al 1994a), largely because they are based on empirical fits to varying experimental data.…”

Section: Cavity Theorymentioning

confidence: 99%

“…In some of the experiments reported in the literature for electron beams, different thicknesses of TLD have been used. Almond and McCray (1970) used LiF TLDs dispensed into cylindrical Teflon capsules of 5 mm diameter and 25 mm length whereas Olivera et al (1994a) used 1 mm thick TLD material. If the energy correction factor depends strongly on the size of the TLD material then the energy correction factor determined by those two groups of authors will be different irrespective of all other factors.…”

Section: Effects Of Cavity Sizementioning

confidence: 99%

“…Some show no energy-dependence (correction factor of unity) relative to Co-60 γ -rays (Shiragai 1977), others correction factors that vary in the range 1.03-1.1 relative to Co-60 γ -rays but with no dependence on the energy of the electron beams McCray 1970, Ogunleye andFregene 1981). The last group show a strong dependence of the energy correction factor on the electron beam energy that varies in the range 1.02-1.14 (Olivera et al 1994a, 1994b, Holt et al 1975. Horowitz (1981) has reviewed some of the data on the energy dependence of LiF TLDs in electron beams.…”

Section: Introductionmentioning

confidence: 99%

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The energy correction factor of LiF thermoluminescent dosemeters in megavoltage electron beams: Monte Carlo simulations and experiments

1996

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The energy correction factor of LiF thermoluminescent dosemeters (TLDs) calibrated in Co-60 gamma-rays and used for measurements in megavoltage electron beams has been determined experimentally and theoretically using Monte Carlo simulations. The experiments show that the energy correction factor of 1 mm thick TLD-100 has an average for both rods and chips which varies from 1.036 +/- 1.3% (1 SD) for 4 MeV electron beams to 1.021 +/- 1.3% (1 SD) for 20 MeV electron beams for measurement performed at dmax in PMMA (Perspex). The results of the Monte Carlo simulations were within 0.6% of the experimental results and ranged from 1.041 +/- 0.9% (1 SD) for 2 MeV electrons to 1.028 +/- 0.8% (1 SD) for 20 MeV electron beams. There was no significant difference in the energy correction factors of LiF TLDs irradiated in PMMA or water by Monte Carlo simulation and experiments. Differences in the energy correction factors between rods and chips of the same thickness were negligible both in the experiments and in Monte Carlo calculation. When the diameter of the LiF TLD micro-rod was increased from 1 to 5 mm, the simulated energy correction factors increased by as much as 5% over this energy range. The energy correction factors changed by up to 4% for irradiation of TLD at depths other than at dmax for a 5 MeV mono-energetic electron beam.

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“…Os fatores de correção de energia sugeridos para feixes de fótons se dividem em 3 grupos: o primeiro mostra a não necessidade de se ter um fator de correção, relativo aos raios γ do 60 Co [Bagne (1977)] ou um fator com valor menor do que 3 % [Nystron et al (1997), Ruden (1977)], para o segundo grupo tem-se uma correção de 4 a 8 % para os raios γ do 60 Co [Almond (1970), Ogunleye et al (1981] e o terceiro, tem-se uma dependência de 7 a 11 % para o mesmo caso [Oliveira (1994)].…”

Section: Dependência Energéticaunclassified

Características dosimétricas para campos pequenos, visando a implementação de um sistema postal de controle de qualidade na radiocirurgia

Calcina¹

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Energy dependence of the response of thermoluminescence dosimeters to photon and electron beams

Cited by 9 publications

References 12 publications

Hydrogel Nanosensors for Colorimetric Detection and Dosimetry in Proton Beam Radiotherapy

Hydrogel Nanosensors for Colorimetric Detection and Dosimetry in Proton Beam Radiotherapy

The energy correction factor of LiF thermoluminescent dosemeters in megavoltage electron beams: Monte Carlo simulations and experiments

Características dosimétricas para campos pequenos, visando a implementação de um sistema postal de controle de qualidade na radiocirurgia

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