Energy demands and the mechanisms of lipid metabolism regulation in Eastern Finns eating the traditional diet

The divergence of genetic complexes in anthropologically related populations with different types of management of natural resources

“…Ïðîaeèâàíèå â óñëîâèÿõ íèçêèõ òåìïåðàòóð òðåáóåò ïîâûøåíèÿ ýíåðãåòè÷åñêèõ òðàò íà ïîääåðaeàíèå îñíîâíîãî îáìåíà, ñîãðåâàíèÿ çà ñ÷¸ò ñîêðàùåíèÿ ìûøö (ñîêðàòèòåëüíûé òåðìîãåíåç) è íåñîêðàòèòåëüíîãî òåðìîãåíåçà, îáåñïå÷èâàþùåãî íà êëåòî÷íîì óðîâíå äîïîëíèòåëüíîå âûäåëåíèå òåïëà ïðè ðàçîáùåíèè ïðîöåññîâ äûõàíèÿ è ôîñôîðèëèðîâàíèÿ. Ñîãëàñíî ïðîâåä¸ííîìó íàìè àíàëèçó è ñòàòèñòè÷åñêèì äàííûì 1920-õ ãîäîâ, ñðåäíèå ýíåðãîòðàòû êîìè-èaeåìöåâ (áåç ó÷¸òà ïîëà è âîçðàñòà) íà 7-15% ïðåâûøàëè òàêîâûå ó êîìè-ïåðìÿêîâ: ó èaeåìöåâ îíè ñîñòàâëÿëè îò 2957 äî 3179 êêàë/ñóò, òîãäà êàê ó êîìèïåðìÿêîâ áûëè áëèçêè ê 2755 êêàë/ñóò [Èâàíîâ-Äÿòëîâ, 1928;Kozlov et al, 2009]. Êîìïåíñàöèÿ çàòðàò âîçìîaeíà òîëüêî çà ñ÷¸ò êàëîðèé, ïîñòóïàþùèõ ñ ïèùåé.…”

The APOE gene ɛ4/ɛ4 “thrifty genotype” and risk of metabolic disorders in populations of the Ural region

“…In the various groups of the Komi, the frequency of this allele varies within 13-22%; in the Mari, its frequency is 15%; and only in Mordvinians is it reduced to a European medium of 10% (Borinskaya et al, 2007). We have analyzed the evolutionary and historical reasons for this in a num ber of works (Borinskaya et al, 2009;Kozlov et al, 2008;Kozlov and Sanina et al, 2009). Briefly, these are as follows.…”

“…At the same time, as historical sources shows, background daily energy expenditure (and, correspondingly, needs) were quite high. According to our reconstructions, the average daily energy con sumption (excluding age and gender) in the northern group of Eastern Finns (Komi, Komi Perm) varied between 2800-3000 kcal/day/person (Kozlov, Sanina et al, 2009;Kozlov et al, 2010).…”