Energy balance related lifestyle factors and risk of endometrial and colorectal cancer among individuals with lynch syndrome: a systematic review

Coletta, Adriana M.; Peterson, Susan K.; Gatus, Leticia A.; Krause, Kate; Schembre, Susan M.; Gilchrist, Susan C.; Pande, Mala; Vilar, Eduardo; You, Yijie; Rodrı́guez-Bigas, Miguel A.; Strong, Larkin L.; Lynch, Patrick M.; Lu, Karen H.; Basen-Engquist, Karen

doi:10.1007/s10689-019-00135-7

Cited by 13 publications

(13 citation statements)

References 51 publications

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“…However, data on the amounts and types of nutrients foraged by free-range birds are lacking and should be further scrutinized to formulate diets that can maintain high poultry production and meat quality. Furthermore, it should be emphasized that free-range birds also consume roots, stems and invertebrates [ 37 ].…”

Section: Discussionmentioning

confidence: 99%

Intake of nutrients (polyunsaturated fatty acids, tocols, and carotenes) and storage efficiency in different slow-growing chickens genotypes reared in extensive systems

Mattioli

Mancinelli²,

Bosco³

et al. 2022

PLoS ONE

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An extensive rearing system (ERS) for poultry requires an outdoor run, which enhances the foraging activity of chickens. Slow-growing (SG) strains are more adapted to ERS than fast-growing (FG); and generally, have higher levels of bioactive compounds in their meat. The aim of this paper was to assess the storage efficiency of n-3 and n-6 polyunsaturated fatty acids (PUFA), tocols and carotenes in the meat of seven commercial SG genotypes (SG1-7). One hundred SG chicks/strain of both sexes were included and their walking activity (High- or Low-W) was classified: SG1-4, HW comprised more than 10% of the time budget, and SG5-7, less than 10% (LW). Chickens were reared in pens (4 pens/strain) with indoor (0.10 m2/bird) and outdoor (4 m2/bird) areas, and they were fed the same diet ad libitum (starter feed for 1–21 d, grower feed from 22 d to slaughter at 81 d). The chickens were weighed weekly; feed consumption and grass intake were also estimated. At 81 days of age, 32 chickens/genotype were selected on the basis of the average weight (1:1, M:F) and slaughtered. The breast, thigh and drumstick meat were excised from 30 carcasses/genotype, sampled and stored at -20°C until analysis. Nutrients (e.g., n-3, n-6, carotenes and tocols) of feed, grass and meat were analyzed. The storage efficiency of nutrients was estimated as the ratio between the amount deposited in the body muscles (OUT) and the dietary intake (feed and grass, IN). The genotype affected chickens foraging behavior and the intake of nutrients. For SG1, SG2 and SG3, more than 50% of the intake of n-3 came from grass, whereas in the other genotypes, less than 20%. Accordingly, chickens that foraged more showed better meat nutritional profiles (less fat, more n-3 and antioxidants), which, in ERS, was ascribed to grass ingestion. However, the storage efficiency of nutrients into meat was inversely correlated with the grass intake: strains with higher grass intake (SG1, SG2, and SG3) had lower storage rates. Several hypotheses were proposed to explain these trends.

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Section: Discussionmentioning

confidence: 99%

Intake of nutrients (polyunsaturated fatty acids, tocols, and carotenes) and storage efficiency in different slow-growing chickens genotypes reared in extensive systems

Mattioli

Mancinelli²,

Bosco³

et al. 2022

PLoS ONE

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“…Most hereditary CRC syndromes display a consistent variability in terms of penetrance and expressivity [ 121 , 122 , 123 , 124 , 125 , 126 , 127 ]. Some have suggested that diet could explain, at least in part, this degree of variability [ 201 , 202 , 203 ]. Few exploratory studies have investigated this hypothesis [ 204 , 205 , 206 ].…”

Section: The Relationship Of Other Risk Factors For Eocrc With Diet and Lifestylementioning

confidence: 99%

The Role of Diet and Lifestyle in Early-Onset Colorectal Cancer: A Systematic Review

Puzzono

Mannucci

Grannò

et al. 2021

Cancers

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The incidence of early-onset colorectal cancer, defined as colorectal cancer occurring in young adults under the age of 50, is increasing globally. Knowledge of the etiological factors in young adults is far from complete. Questionable eoCRCs’ exogenous factors are represented by processed meat, sugary drinks, alcohol, Western dietary pattern, overweight and obesity, physical inactivity, and smoking, though with heterogeneous results. Therefore, we performed a systematic review to summarize the current evidence on the role of diet and lifestyle as eoCRC risk factors. We systematically searched PubMed, Scopus, and EMBASE up to July 2021, for original studies evaluating diet, alcohol, physical activity, BMI, and smoking in eoCRC and included twenty-six studies. Indeed, the exogenous factors could represent modifiable key factors, whose recognition could establish areas of future interventions through public health strategies for eoCRC primary prevention. Additionally, we discussed the role of additional non-modifiable risk factors, and of epigenetic regulation and microbiota as mediators of the eoCRC triggered by diet and lifestyle.

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“…Among LS patients, lifestyle-related factors have also been associated with cancer risk. A recent systematic review has shown that early-adulthood overweight/obese weight status and adulthood weight gain may be associated with increased colorectal cancer risk in LS patients [14]. Moreover, a recent meta-analysis has shown that obesity has been associated with an increased risk for colorectal cancer, but only in men with LS [15].…”

Section: Introductionmentioning

confidence: 99%

Determinants of adherence to recommendations on physical activity, red and processed meat intake, and body weight among lynch syndrome patients

et al. 2022

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This study aimed to identify determinants of adherence to lifestyle and body weight recommendations for cancer prevention among Lynch Syndrome (LS) patients. Cross-sectional baseline data of LS patients participating in the Lifestyle & Lynch (LiLy) study was used to assess determinants of adherence to the World Cancer Research Fund cancer prevention recommendations on body weight, physical activity, and red and processed meat intake. Adherence and potential determinants of adherence were assessed using questionnaires. Multivariable logistic regression analyses were conducted to identify determinants of adherence. Of the 211 participants, 50.2% adhered to the body weight recommendation, 78.7% adhered to the physical activity recommendation, and 33.6% adhered to the red and processed meat recommendation. Being younger and having a higher level of education were associated with adherence to the recommendation on body weight. Having knowledge about the recommendation was associated with adherence to the recommendations on physical activity and red and processed meat. Results confirm that knowledge about recommendations for cancer prevention is an important determinant for adherence and suggest that strategies to increase knowledge should be included in lifestyle promotion targeted at LS patients, along with behavior change techniques influencing other modifiable determinants.

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Energy balance related lifestyle factors and risk of endometrial and colorectal cancer among individuals with lynch syndrome: a systematic review

Cited by 13 publications

References 51 publications

Intake of nutrients (polyunsaturated fatty acids, tocols, and carotenes) and storage efficiency in different slow-growing chickens genotypes reared in extensive systems

Intake of nutrients (polyunsaturated fatty acids, tocols, and carotenes) and storage efficiency in different slow-growing chickens genotypes reared in extensive systems

The Role of Diet and Lifestyle in Early-Onset Colorectal Cancer: A Systematic Review

Determinants of adherence to recommendations on physical activity, red and processed meat intake, and body weight among lynch syndrome patients

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