With the arises of Industry 4.0, numerous concepts have emerged, one of the main concepts is the Digital Twin (DT). DT is being widely used nowadays, however, as there are several uses in the existing literature, the understanding of the concept and its functioning can be diuse. The main goal of this paper is to provide a review of the existing literature, to clarify the concept, operation and main characteristics of DT. Also, to introduce the most current operating, communication and usage trends related to this technology. And present the performance of the synergy between DT and MAS (Multi-Agent System) technologies, through a computer science approach.