Endovenous Valve Transfer for Chronic Deep Venous Insufficiency

Phillips, Mark N.; Dijkstra, Martijn; Khin, Nyan Y; Lane, Rodney J.

doi:10.1016/j.ejvs.2013.05.013

Cited by 4 publications

(3 citation statements)

References 22 publications

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“…8,12,14,50 These studies suggest that a finite number of VEHTCs can make a difference in a patient’s outcome.…”

Section: Advantages and Challenges Of The Approachmentioning

confidence: 99%

“…6–8 For superficial veins, nonsurgical treatment options include leg elevation, compression stockings, and venoactive medications. Surgical options include vein stripping or vein sealing, with the latter using radiofrequency or laser energy or ultrasound-guided foam sclerotherapy.…”

Section: Chronic Deep Venous Insufficiencymentioning

confidence: 99%

“…53 This method can be accomplished using a commercially available kit (Venocuff II, Imthage, Australia) and it has been shown to work fairly well in specific clinical cases. 8,54 Therefore, VEHTC can be designed to serve as both a stent and an actively contracting pump.…”

Section: Advantages and Challenges Of The Approachmentioning

confidence: 99%

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Thinking Outside the Heart

Sarvazyan

2014

J Cardiovasc Pharmacol Ther

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This article considers the use of autologous stem cell-derived cardiomyocytes as a novel means to aid venous return. The approach consists of creating external cuffs of engineered heart tissue around vein segments with incompetent or poorly competent valves. The engineered heart tissue cuff prevents distention of the impaired vein segments and aids unidirectional flow by its rhythmic contractions. There appear to be no fundamental limitations to this approach as feasibility of all of the individual components has already been shown. Here, we underline the clinical need for novel ways to treat chronic deep venous insufficiency, review previous research that enabled this approach, consider potential designs of engineered heart tissue cuffs, and outline its advantages and future challenges.

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“…8,12,14,50 These studies suggest that a finite number of VEHTCs can make a difference in a patient’s outcome.…”

Section: Advantages and Challenges Of The Approachmentioning

confidence: 99%

Section: Chronic Deep Venous Insufficiencymentioning

confidence: 99%