2015
DOI: 10.1016/j.jocn.2014.05.032
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Abstract: Severe acute basilar artery occlusion (BAO) has a high mortality rate but as yet no effective treatment has been developed. This study aimed to evaluate the feasibility and safety of combined mechanical thrombectomy, intra-arterial thrombolysis, and emergent stent placement for patients with severe acute BAO. Eighteen patients who were unconscious after confirmed onset of BAO and who were given arterial interventional treatment from March 2011 to June 2013 at our department were included in this study. The mea… Show more

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Cited by 16 publications
(20 citation statements)
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“…However, those studies all focused on anterior circulation acute stroke; there are no RCT, to our knowledge, on the safety and efficacy of using stent retrievers MT for acute BAO. Further, only a few small-sample-sized retrospective studies have reported clinical findings of MT with stent retrievers in acute BAO [17][18][19][20][21].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…However, those studies all focused on anterior circulation acute stroke; there are no RCT, to our knowledge, on the safety and efficacy of using stent retrievers MT for acute BAO. Further, only a few small-sample-sized retrospective studies have reported clinical findings of MT with stent retrievers in acute BAO [17][18][19][20][21].…”
Section: Discussionmentioning
confidence: 99%
“…In that study, good functional outcome (mRS 0-2) was achieved in 48% (12/25) of patients, and 88% (22/25) survived to 3 months. Finally, Wang et al [21] reported 18 severe acute BAOs treated with MT. Successful recanalization (TICI 3 or 2b) was obtained in 94.4% (17/18) of patients, with a mean of 1.5 passes.…”
Section: Discussionmentioning
confidence: 99%
“…Espinosa de Rueda et al [20] reported, in a series of 18 patients with acute BAO who were directly treated with mechanical thrombectomy with either the Solitaire stent (10/18) or the Trevo stent (8/10), a good outcome was recorded in 50% (9/18), and the mortality rate was 22.3% at 3 months. Wang et al [21] in his personal series of 18 patients with BAO all treated with mechanical thrombectomy (10 patients only with mechanical thrombectomy, 8 patients treated in addition with intra-arterial thrombolysis) reported a recanalization rate of 94.4% with a mortality rate, according to the literature, of 27.8%. The literature shows a contrast between a high recanalization rate and clinically good outcome rate [7,8,11,[19][20][21].…”
Section: Discussionmentioning
confidence: 99%
“…Wang et al [21] in his personal series of 18 patients with BAO all treated with mechanical thrombectomy (10 patients only with mechanical thrombectomy, 8 patients treated in addition with intra-arterial thrombolysis) reported a recanalization rate of 94.4% with a mortality rate, according to the literature, of 27.8%. The literature shows a contrast between a high recanalization rate and clinically good outcome rate [7,8,11,[19][20][21]. These findings might be attributable to the small personal series, but also to different factors indicated as predictors of outcome as initial NIHSS score, age, time from onset to treatment, thrombus localization [2,3,[22][23][24].…”
Section: Discussionmentioning
confidence: 99%
“…Although anticoagulation and antiplatelet method have been widely used in the clinic by many doctors, 80%-90% patients still can not avoid death5. Recent reports have showed that thrombolytic therapy can effectively decrease the mortality rate and greatly improve patients' quality of life 6.…”
Section: Introductionmentioning
confidence: 99%