“…The rate of perioperative complications has ranged from 4.2% to 17.2%. 9,10,12,[14][15][16][17] The rate of perioperative complications was 17% in the present study, similar to that reported in previous studies. In previous studies, the rate of procedure-related mortality was 2.9%-9%, and procedure-related morbidity was 8%.…”
Section: Discussionsupporting
confidence: 92%
“…In previous reports of coil embolization for DACA aneurysms, the rate of immediate angiographic CO has ranged from 23.1% to 100%. 9,10,12,14–17 In the present study, the rate of immediate angiographic CO was 8.3%, and the rate of immediate angiographic CO and NR combined was 66.7%. However, the rate of angiographic CO at 1 year after the procedure was 75%, and rupture caused by treated aneurysm was not detected during the follow-up period.…”
Section: Discussionsupporting
confidence: 47%
“…The rate of re-treatment generally ranged from 8% to 30%. 9,10,12,14–17 The rate of re-treatment was 16.7% in the present study.…”
Section: Discussionsupporting
confidence: 46%
“…11–14 There are several reports of coil embolization for unruptured DACA aneurysms in the literature. 9,10,12,14–17…”
Section: Introductionmentioning
confidence: 99%
“…[11][12][13][14] There are several reports of coil embolization for unruptured DACA aneurysms in the literature. 9,10,12,[14][15][16][17] Although antiplatelet therapy is widely used for prevention of thromboembolic events, these events continue to be an important complication of coil embolization for cerebral aneurysms. Thromboembolic events can manifest as follows: 1) thrombus formation observed during the procedure; 2) clinical ischemic symptoms, recognized as ischemia on neurological evaluation, which can be a transient ischemic attack or a permanent ischemic infarction; and 3) silent ischemic events, abnormalities detected by diffusion-weighted magnetic resonance imaging (DW-MRI).…”
Background Distal anterior cerebral artery (DACA) aneurysms are rare, and endovascular treatment of these aneurysms is challenging. Thromboembolic events, including silent ischemic events, are one of the most important complications of coil embolization for cerebral aneurysms. The treatment outcomes and predictors of silent ischemic events in coil embolization for unruptured DACA aneurysms were investigated, focusing on the morphological characteristics of aneurysms, especially the inflow angle (IA) and global outflow angle (GOA). Methods A total of 12 patients with 12 unruptured DACA aneurysms, treated with coil embolization at our institute, were retrospectively investigated. Predictors for silent ischemic events were evaluated by comparing diffusion-weighted imaging (DWI)-positive and DWI-negative patients. Results Silent ischemic events detected on DWI were observed in eight aneurysms (66.7%). Comparison of the morphological characteristics of aneurysms between the two groups showed a significantly smaller GOA in the DWI-positive group than in the DWI-negative group (172.6 ± 17.7° vs. 216.8 ± 16.8°, P < 0.01). A multivariate analysis showed that GOA <195° was a significant predictor of silent ischemic events ( P = 0.04; odds ratio: 23.62; 95% confidence interval: 1.11–490.39). Conclusion A small GOA was a significant predictor of silent ischemic events after coil embolization for unruptured DACA aneurysms. While some patients can be treated safely with minimally invasive coil embolization, it is necessary to consider surgical clipping in patients at high risk of thromboembolic events with coil embolization.
“…The rate of perioperative complications has ranged from 4.2% to 17.2%. 9,10,12,[14][15][16][17] The rate of perioperative complications was 17% in the present study, similar to that reported in previous studies. In previous studies, the rate of procedure-related mortality was 2.9%-9%, and procedure-related morbidity was 8%.…”
Section: Discussionsupporting
confidence: 92%
“…In previous reports of coil embolization for DACA aneurysms, the rate of immediate angiographic CO has ranged from 23.1% to 100%. 9,10,12,14–17 In the present study, the rate of immediate angiographic CO was 8.3%, and the rate of immediate angiographic CO and NR combined was 66.7%. However, the rate of angiographic CO at 1 year after the procedure was 75%, and rupture caused by treated aneurysm was not detected during the follow-up period.…”
Section: Discussionsupporting
confidence: 47%
“…The rate of re-treatment generally ranged from 8% to 30%. 9,10,12,14–17 The rate of re-treatment was 16.7% in the present study.…”
Section: Discussionsupporting
confidence: 46%
“…11–14 There are several reports of coil embolization for unruptured DACA aneurysms in the literature. 9,10,12,14–17…”
Section: Introductionmentioning
confidence: 99%
“…[11][12][13][14] There are several reports of coil embolization for unruptured DACA aneurysms in the literature. 9,10,12,[14][15][16][17] Although antiplatelet therapy is widely used for prevention of thromboembolic events, these events continue to be an important complication of coil embolization for cerebral aneurysms. Thromboembolic events can manifest as follows: 1) thrombus formation observed during the procedure; 2) clinical ischemic symptoms, recognized as ischemia on neurological evaluation, which can be a transient ischemic attack or a permanent ischemic infarction; and 3) silent ischemic events, abnormalities detected by diffusion-weighted magnetic resonance imaging (DW-MRI).…”
Background Distal anterior cerebral artery (DACA) aneurysms are rare, and endovascular treatment of these aneurysms is challenging. Thromboembolic events, including silent ischemic events, are one of the most important complications of coil embolization for cerebral aneurysms. The treatment outcomes and predictors of silent ischemic events in coil embolization for unruptured DACA aneurysms were investigated, focusing on the morphological characteristics of aneurysms, especially the inflow angle (IA) and global outflow angle (GOA). Methods A total of 12 patients with 12 unruptured DACA aneurysms, treated with coil embolization at our institute, were retrospectively investigated. Predictors for silent ischemic events were evaluated by comparing diffusion-weighted imaging (DWI)-positive and DWI-negative patients. Results Silent ischemic events detected on DWI were observed in eight aneurysms (66.7%). Comparison of the morphological characteristics of aneurysms between the two groups showed a significantly smaller GOA in the DWI-positive group than in the DWI-negative group (172.6 ± 17.7° vs. 216.8 ± 16.8°, P < 0.01). A multivariate analysis showed that GOA <195° was a significant predictor of silent ischemic events ( P = 0.04; odds ratio: 23.62; 95% confidence interval: 1.11–490.39). Conclusion A small GOA was a significant predictor of silent ischemic events after coil embolization for unruptured DACA aneurysms. While some patients can be treated safely with minimally invasive coil embolization, it is necessary to consider surgical clipping in patients at high risk of thromboembolic events with coil embolization.
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