Endovascular Stents in Pulmonary Valve and Artery in Swine: Feasibility Study of MR Imaging–guided Deployment and Postinterventional Assessment

Küehne, Titus; Saeed, M. A.; Higgins, Charles B.; Gleason, Kelly; Krombach, Gabriele A.; Weber, O.; Martin, Alastair J.; Turner, Daniel R.; Teitel, David; Moore, Phillip

doi:10.1148/radiol.2262011639

Cited by 73 publications

(57 citation statements)

References 27 publications

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“…[12][13][14] In the present study, we used this approach to perform invasive RV pressure measurements with flow-directed catheters guided under MR fluoroscopy. Simultaneously, ventricular volumes were assessed by use of cine MRI.…”

mentioning

confidence: 99%

Magnetic Resonance Imaging Analysis of Right Ventricular Pressure-Volume Loops

Küehne

Yilmaz²,

Steendijk³

et al. 2004

Circulation

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324

117

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Background-The aims of this study were to validate MRI-derived right ventricular (RV) pressure-volume loops for assessment of RV myocardial contractility and then to apply this technique in patients with chronic RV pressure overload for assessment of myocardial contractility, ventricular pump function, and VA coupling. Methods and Results-Flow-directed catheters were guided under MR fluoroscopy (1.5 T) into the RV for invasive pressure measurements. Simultaneously, ventricular volumes and myocardial mass were assessed from cine MRI. From sampled data, RV pressure-volume loops were constructed, and maximal ventricular elastance indexed to myocardial mass (E max_i ) was derived by use of a single-beat estimation method. This MRI method was first validated in vivo (6 swine), with conductance techniques used as reference. Bland-Altman test showed good agreement between methods (E max_i ϭ5.1Ϯ0.5 versus 5.8Ϯ0.7 mm Hg · mL Ϫ1 · 100 g

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mentioning

confidence: 99%

Magnetic Resonance Imaging Analysis of Right Ventricular Pressure-Volume Loops

Küehne

Yilmaz²,

Steendijk³

et al. 2004

Circulation

Self Cite

324

117

View full text Add to dashboard Cite

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“…The development and application of MRI as a guidance tool for endovascular and endoluminal interventions is furthermore motivated by the potential of MRI to acquire relevant morphologic and functional information that cannot be retrieved with other methods. In particular, the measurement of blood flow and perfusion (for example, after stent implantation in the carotid or renal artery) (19) or diffusion (eg, during embolizations) (20) might enable an early evaluation of the therapeutic success during the intervention, thus enabling therapeutically relevant decision-making with the patient still on the table.…”

Section: Endovascular Interventionsmentioning

confidence: 99%

“…In vessels with atherosclerotic plaques interventional MRI has the potential to visualize the morphology of both the vessel wall and the surrounding tissue (2,9,19,(21)(22)(23)(24)(25), whereas conventional angiography is only able to delineate the vessel lumen. The advantages of this information are clear when one considers that the dangers associated with atherosclerosis are not only caused by luminal narrowing but are also dependent on the structure of the vessel wall.…”

Section: Endovascular Interventionsmentioning

confidence: 99%

“…An advantage of utilizing microcoils is the possibility to use the MR signal not only for instrument tracking but also for endovascular imaging or functional studies (19,(23)(24)(25). If, for example, the signals of two solenoid coils are combined, both tracking of the catheter as well as high-resolution imaging of the vessel wall is possible (9,54).…”

Section: Tracking and Profiling Rf Coilsmentioning

confidence: 99%

“…A possible candidate for such an application is the MR-guided targeted injection of cellular material (eg, stem cells or myoblasts) into the vessel wall (81) or the infarcted myocardium (2,19). Under conventional fluoroscopy neither the differentiation between infarcted and viable myocardium nor the reliable tracking of the injected cells is possible (82).…”

Section: Endovascular Applicationsmentioning

confidence: 99%

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MR‐guided intravascular interventions: Techniques and applications

Bock

Wacker

2008

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) offers several advantages over other imaging modalities that make it an attractive imaging tool for diagnostic and therapeutic procedures. This tremendous potential of MRI has provided the rationale for increased attention toward MR-guided endovascular interventions. MR guidance has been used recently to navigate endovascular catheters and deliver stents, vena cava filters, embolization materials, and septum closure devices. However, its potential goes beyond just copying existing procedures toward the development of new minimally invasive techniques that cannot be performed with conventional guiding techniques. Because of technical limitations and safety issues associated with some of the currently available devices, a limited number of clinical studies have been performed so far. The overall success for this developing field requires considerable interdisciplinary research within both the interventional and the MR community. Only through a combined effort can this complex technology find its way into clinical practice. This review discusses the hardware and software improvements that have helped to advance endovascular interventions under MR imaging guidance from a pure research tool to become a clinical reality. In addition, technical and safety issues specific to endovascular MR image guidance will be described and practical applications will be shown that take advantage of the benefits of MR for endovascular interventions.

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