Endovascular Recanalization of Thromboangiitis Obliterans (Buerger’s Disease) in Twenty-Eight Consecutive Patients and Combined Antegrade–Retrograde Intervention in Eight Patients

Fırat, Ali; Igus, Behlul

doi:10.1007/s00270-019-02193-x

Cited by 14 publications

(6 citation statements)

References 32 publications

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“…On the other hand, endovascular treatment has recently emerged as an alternative for patients with TAO. In previous studies, angiographic success with endovascular recanalization (ER) for TAO was achieved in 76-96% of the infrapopliteal lesions, and the primary patency rate at 12 months was 72-84% 24,25) . Regarding CLI due to TAO, comparative studies have revealed that patients in the ER group exhibit a much higher incidence of immediate failure (36-66%) than those in the bypass surgery group (15%).…”

Section: Discussionmentioning

confidence: 99%

Critical Limb Ischemia due to Buerger Disease Successfully Treated with Endovascular Recanalization and Distal Bypass

Kitai,

Kanayama,

Suhara

et al. 2023

International Journal of Surgical Wound Care

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Buerger disease or thromboangiitis obliterans is a non-atherosclerotic, segmental, inflammatory, peripheral arterial occlusive disease in young male smokers. Revascularization via endovascular treatment and/or bypass surgery is less common and is technically challenging in patients with Buerger disease. Herein, we report the case of a 30-year-old male patient who underwent endovascular treatment followed by bypass surgery, which successfully salvaged his critically ischemic limbs. This case demonstrates that a revascularization strategy for critical limb ischemia due to Buerger disease could be beneficial for limb salvage. To achieve effective limb salvage, a collaborative approach among endovascular specialists, vascular surgeons, and reconstructive surgeons is recommended.

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Section: Discussionmentioning

confidence: 99%

Critical Limb Ischemia due to Buerger Disease Successfully Treated with Endovascular Recanalization and Distal Bypass

Kitai,

Kanayama,

Suhara

et al. 2023

International Journal of Surgical Wound Care

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“…En el tratamiento endovasuclar de la enfermedad de Buerger, se ha determinado, según varios estudios, que la tasa de éxito técnico es alta, del 87,5% (Firat, 2019), 91% (Kacmaz, 2019), 82% (Uyanik, 2021). Y la tasa de salvamento de la extremidad del 100% (Kacmaz, 2019), 92% (Modaghegh, 2017), 87,5% (Rodoplu, 2020), 93,3 % (Uyanik, 2021.…”

Section: Oclusiones Arteriales Infrapoplíteasunclassified

Enfermedad de buerger presentación de caso y revisión de la literatura

Gómez

Hermenejildo²,

Bajaña³

et al. 2023

Ciencia Latina

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La tromboangeítis obliterante o también conocida como enfermedad de Buerger, es una enfermedad rara que es considerada como un trastorno de proceso no aterosclerótico, inflamatoria, que predomina en medianos y pequeños vasos, principalmente a nivel de brazos (infrabraquiales) y de piernas (infrapoplíteos). Generalmente llevan a una trombosis oclusiva, provocando isquemia y posteriormente lesiones ulcerosas de localización predominantemente distal, que muchas veces llega a la amputación debido a su fuerte compromiso. Con mayor frecuencia afecta a hombres jóvenes, y es asociada directa e íntimamente con el tabaquismo. Aun en la actualidad se continúa sin poder determinar la etiología de esta enfermedad, siendo esta patología motivo de constante investigación, su aparición y desarrollo se encuentra íntimamente asociada al consumo excesivo de tabaco como factor principal dentro del proceso etiopatogénico. El objetivo principal de este trabajo radica en presentar un caso, y demostrar, una vez más mediante la evidencia, como el consumo de tabaco puede predisponer a la aparición y desarrollo de esta enfermedad, así como también realizar una revisión de la bibliografía para evidenciar lo relevante de esta enfermedad.

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“…In recent series, however, outcomes following percutaneous transluminal angioplasty (PTA) have been more favorable with technical success and limb salvage rates as high as 92-96% and 92-100%, respectively. [25][26][27][28] Although reintervention is required in approximately 30% of endovascular cases, 25 outcomes following open vascular reconstruction are significantly worse, partially due to lack of suitable venous conduits. In a retrospective study of 110 patients with Buerger's disease, primary graft patency was 41% at 1 year, 32% at 5 years, and 30% at 10 years for 46 bypasses performed.…”

Section: Current Surgical Therapymentioning

confidence: 99%

Therapeutic angiogenesis in Buerger’s disease: reviewing the treatment landscape

Ribieras

Ortiz

Liu

et al. 2022

Therapeutic Advances in Rare Disease

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Thromboangiitis obliterans, also known as Buerger’s disease, is a rare inflammatory vasculitis that predominantly develops in smokers and characteristically affects the small- and medium-sized peripheral arteries and veins. Patients typically present with extremity claudication, but symptoms may progress to rest pain and tissue loss, especially in those unable to abstain from tobacco use. Unfortunately, traditional medical treatments are largely ineffective and due to the small caliber of affected vessels and lack of suitable distal targets or venous conduits, endovascular and open surgical approaches are often not possible. Eventually, a significant number of patients require major amputation. For these reasons, much research effort has been made in developing techniques of therapeutic angiogenesis to improve limb perfusion, both for atherosclerotic peripheral arterial disease and the smaller subset of patients with critical limb ischemia due to Buerger’s disease. Neovascularization in response to ischemia relies on a complex interplay between the local tissue microenvironment and circulating stem and progenitor cells. To date, studies of therapeutic angiogenesis have therefore focused on exploiting known angiogenic factors and stem cells to induce neovascularization in ischemic tissues. This review summarizes the available clinical data regarding the safety and efficacy of various angiogenic therapies, notably injection of naked DNA plasmids, viral gene constructs, and cell-based preparations, and describes techniques for potentiating in vivo efficacy of gene- and cell-based therapies as well as ongoing developments in exosome-based cell-free approaches for therapeutic angiogenesis. Plain Language Title and Summary A review of available and emerging treatments for improving blood flow and wound healing in patients with Buerger’s disease, a rare disorder of blood vessels Buerger’s disease is a rare disorder of the small- and medium-sized blood vessels in the arms and legs that almost exclusively develops in young smokers. Buerger’s disease causes inflammation in arteries and veins, which leads to blockage of these vessels and reduces blood flow to and from the extremities. Decreased blood flow to the arms and legs can lead to development of nonhealing wounds and infection for which some patients may eventually require amputation. Unfortunately, traditional medical and surgical treatments are not effective in Buerger’s disease, so other methods for improving blood flow are needed for these patients. There are several different ways to stimulate new blood vessel formation, both in humans and animal models. The most common treatments involve injection of DNA or viruses that express genes related to blood vessel formation or, alternatively, stem cell–based treatments that help regenerate blood vessels and repair wound tissue. This review explores how safe and effective these various treatments are and describes recent research developments that may lead to better therapies for patients with Buerger’s disease and other vascular disorders.

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Endovascular Recanalization of Thromboangiitis Obliterans (Buerger’s Disease) in Twenty-Eight Consecutive Patients and Combined Antegrade–Retrograde Intervention in Eight Patients

Cited by 14 publications

References 32 publications

Critical Limb Ischemia due to Buerger Disease Successfully Treated with Endovascular Recanalization and Distal Bypass

Critical Limb Ischemia due to Buerger Disease Successfully Treated with Endovascular Recanalization and Distal Bypass

Enfermedad de buerger presentación de caso y revisión de la literatura

Therapeutic angiogenesis in Buerger’s disease: reviewing the treatment landscape

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