Endovascular Pressure Measurements to Assess the Functional Severity of Mesenteric Arterial Stenoses

Dijk, Louisa J. van; Terlouw, Luke G.; Noord, Désirée Leemreis van; Bijdevaate, Diederik; Bruno, Marco J.; Moelker, Adriaan

doi:10.1016/j.jvir.2019.10.019

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…Diabetic peripheral neuropathy, characterized by perivascular neuropathy, is reported to be involved in vascular disorders associated with diabetes ( Olesen et al, 2021 ). The mesenteric artery, a part of the splanchnic circulation system, is involved in the regulation of arterial pressure ( van Dijk et al, 2020 ). The iliac artery is mainly responsible for blood supply to the lower extremities and pelvic organs ( Maier et al, 2020 ).…”

Section: Effects Of Berberine On Vascular Diseasesmentioning

confidence: 99%

Berberine: A Review of its Pharmacokinetics Properties and Therapeutic Potentials in Diverse Vascular Diseases

Peng

et al. 2021

Front. Pharmacol.

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Traditional Chinese medicine plays a significant role in the treatment of various diseases and has attracted increasing attention for clinical applications. Vascular diseases affecting vasculature in the heart, cerebrovascular disease, atherosclerosis, and diabetic complications have compromised quality of life for affected individuals and increase the burden on health care services. Berberine, a naturally occurring isoquinoline alkaloid form Rhizoma coptidis, is widely used in China as a folk medicine for its antibacterial and anti-inflammatory properties. Promisingly, an increasing number of studies have identified several cellular and molecular targets for berberine, indicating its potential as an alternative therapeutic strategy for vascular diseases, as well as providing novel evidence that supports the therapeutic potential of berberine to combat vascular diseases. The purpose of this review is to comprehensively and systematically describe the evidence for berberine as a therapeutic agent in vascular diseases, including its pharmacological effects, molecular mechanisms, and pharmacokinetics. According to data published so far, berberine shows remarkable anti-inflammatory, antioxidant, antiapoptotic, and antiautophagic activity via the regulation of multiple signaling pathways, including AMP-activated protein kinase (AMPK), nuclear factor κB (NF-κB), mitogen-activated protein kinase silent information regulator 1 (SIRT-1), hypoxia-inducible factor 1α (HIF-1α), vascular endothelial growth factor phosphoinositide 3-kinase (PI3K), protein kinase B (Akt), janus kinase 2 (JAK-2), Ca2+ channels, and endoplasmic reticulum stress. Moreover, we discuss the existing limitations of berberine in the treatment of vascular diseases, and give corresponding measures. In addition, we propose some research perspectives and challenges, and provide a solid evidence base from which further studies can excavate novel effective drugs from Chinese medicine monomers.

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Section: Effects Of Berberine On Vascular Diseasesmentioning

confidence: 99%

Berberine: A Review of its Pharmacokinetics Properties and Therapeutic Potentials in Diverse Vascular Diseases

Peng

et al. 2021

Front. Pharmacol.

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“…The performance characteristics of CTA can be summarized as fair, and similar to CDU performance [5]. To pursue and report pressure measurements before and after deployment of endoprosthesis is very important in the management of patients with suspected chronic mesenteric ischemia as MAP gradients reflect clinical severity of SMA stenosis [10]. A successful mesenteric revascularization should not only be accompanied by reduction of MAP gradient towards zero, but also to immediate symptom relief [11].…”

Section: Discussionmentioning

confidence: 99%

Validation of computed tomography angiography using mean arterial pressure gradient as a reference in stented superior mesenteric artery

et al. 2020

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Purpose The aim of this prospective study was to validate the diagnostic performance of computed tomography angiography (CTA) in endoprosthesis stenosis in the superior mesenteric artery (SMA) using mean arterial pressure (MAP) gradients during angiography as a reference method. Methods Twenty-nine patients with mesenteric atherosclerotic disease underwent 45 paired measurements of endoprosthesis stenosis in the SMA with CTA and MAP gradients between March 2009 and July 2015. The grade of endoprosthesis stenosis in the SMA at CTA using the TeraRecon Aquarius workstation was correlated with MAP gradients. Results Grade of endoprosthesis stenosis in the SMA (r = 0.37, p = 0.013) correlated with MAP gradients. The intraclass correlations between the first and second CTA rater was 0.76 (95% CI 0.56–0.87) for estimation of grade of endoprosthesis stenosis in the SMA. The area under the receiver operating characteristics curve was 0.79 for diagnosis of significant endoprosthesis stenosis in the SMA at CTA for different threshold values using MAP gradient of ≥ 10 mmHg as reference. Sensitivity, specificity and positive predictive value for endoprosthesis stenosis in the SMA ≥ 50% at CTA were 52.4% (95% CI 31.0–73.7), 87.5% (95% CI 74.3–100.0) and 78.6 (95% CI 57.1–1.00), respectively. Conclusion Grading endoprosthesis stenosis in the SMA with CTA performed fair when using trans-stenotic MAP gradient as reference. Software development towards reduction of endoprosthesis artefacts may result in more accurate CTA assessment of the narrowest part.

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“…в сочетании со стенозированием просвета ≥50 % по диаметру могут быть использованы для определения критического стеноза [39][40][41][42][43]. Существуют работы [44], в которых используется отношение артериального давления за стенозом к давлению в аорте, при этом использование вазодилататоров улучшает прогностическую ценность исследования.…”

Section: критический стеноз мезентериальных артерийunclassified

On the issue of critical arterial stenosis

Suprunovich¹,

Bedrov²,

Vrabiy³

et al. 2021

The Scientific Notes of the Pavlov university

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Cardiovascular disease (CVD) is the leading cause of death worldwide. The main contribution to the structure of mortality from CVD is made by atherosclerosis. Indications for surgical treatment of patients with diseases caused by atherosclerotic lesions of the arteries are set taking into account the degree of their stenosis. Angiography has been considered the gold standard for screening patients with CVD for many years. Numerous studies carried out over the past several decades have revealed the weak side of this method in assessing the significance of borderline stenosis. Therefore, to analyze such changes, functional tests were introduced to clarify the indications for surgical intervention. Currently, criteria for the significance of stenosis of the iliac, renal and coronary arteries have been determined. The significance of stenosis of the arteries supplying the brain and intestines is still a matter of debate and requires further study.

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Endovascular Pressure Measurements to Assess the Functional Severity of Mesenteric Arterial Stenoses

Cited by 3 publications

References 19 publications

Berberine: A Review of its Pharmacokinetics Properties and Therapeutic Potentials in Diverse Vascular Diseases

Berberine: A Review of its Pharmacokinetics Properties and Therapeutic Potentials in Diverse Vascular Diseases

Validation of computed tomography angiography using mean arterial pressure gradient as a reference in stented superior mesenteric artery

On the issue of critical arterial stenosis

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