Endovascular Aneurysm Repair or Open Aneurysm Repair for the Treatment of Abdominal Aortic Aneurysm – The Latest Update

Kulig, Piotr; Lewandowski, Krzysztof; Ziaja, Damian; Zaniewski, Maciej; Kulig, Jan

doi:10.1515/pjs-2016-0047

Cited by 3 publications

(3 citation statements)

References 37 publications

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“…In summary, all current treatments for AA dependent on mechanical intervention. However, when most AAs are detected, they are below the threshold for repair, leading to a significant observation period during which there is currently no non-surgical therapy to prevent or slow AA expansion [15], highlighting a real need for better understanding of the potential mechanisms involved in the pathogenesis of AA.…”

Section: The Current Treatments For Aortic Aneurysmmentioning

confidence: 99%

Diverse roles of macrophage polarization in aortic aneurysm: destruction and repair

Cheng

Zhou

et al. 2018

J Transl Med

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Aortic aneurysm (AA) is defined as an enlargement of the aorta greater than 1.5 times its normal size. Early diagnosis of AA is challenging and mortality of AA is high. Curative pharmacological treatments for AA are still lacking, highlighting the need for better understanding of the underlying mechanisms of AA progression. Accumulating studies have proven that the polarization state of circulating monocyte-derived macrophages plays a crucial role in regulating the development of AA. Distinct macrophage subtypes display different functions. Several studies targeting macrophage polarization during AA formation and progression showed potential treatment effects. In this review, we focus on the recent advances of research on macrophage polarization in the progression of AA and propose that targeting macrophage polarization could hold great promise for preventing and treating AA.

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Section: The Current Treatments For Aortic Aneurysmmentioning

confidence: 99%

Diverse roles of macrophage polarization in aortic aneurysm: destruction and repair

Cheng

Zhou

et al. 2018

J Transl Med

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“…Closely related to atherosclerosis is another chronic disease affecting the elderly -ischaemic heart disease, caused by atherosclerosis of the coronary arteries. As a result of their narrowing, there is a reduced supply of oxygen to the heart muscle, relative to its demand [18]. The disease may be latent or overt, manifesting as chest pain (angina), which may be non-specific in seniors.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of chronic diseases among residents of care and treatment institutions in Wrocław

Wróblewska,

Motyl,

Król

et al. 2023

Med Srod.

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Introduction and Objective. Chronic diseases are the most common cause of psycho-physical disability in seniors, and the reason for increased levels of dependency on others. Multimorbidity, which is closely related to multi-drug use, can be found in most elderly people. The concomitant coexistence of chronic diseases causes difficulties in diagnosis, ambiguity in clinical images, contributing to the development of severe complications and generating resistance to treatment. The aim of study was to analyse the frequency of chronic diseases among nursing home residents, and the impact on their daily functioning. Material and methods. The study was conducted on a group of 120 residents in care and treatment facilities in Wrocław. An author's questionnaire and the Barthel Scale were used. Respondents were predominantly aged 81-90 years (42%), mainly women (78%), with vocational education (57%), living on a pension (60.8%), and living in the city (62%). Results. According to their BMI, 58% of respondents were found to be overweight. The majority were partially dependent on the care of others (72%), required constant nursing care (73%), and their families were not care-efficient (67%). Respondents were characterised by multi-morbidity, with the most common conditions being atherosclerosis (58%), hypertension (43%), stroke (28%) and diabetes (18%), and complaints of feeling heavy in the legs (51%), rapid fatigue (48%), pain (44%) and dizziness (42%), which hindered daily functioning (73%). Conclusions. Inappropriate health behaviours influence the development of chronic diseases. The course of chronic diseases causes dependency on others in respondents. Disability results in the need for round-the-clock care for the senior citizen.

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“…The traditional open laparotomy used for surgical repair has been gradually replaced by less invasive interventions, such as the placement of endovascular stents (endovascular aneurysm repair -EVAR). The latter procedure is associated with less traumatic stress and lower pain scores, leading to shorter hospitalization and faster recovery in comparison to open surgery [1][2][3][4]. Reports from the United States show that EVAR has become the most frequently used type of intervention for AAA [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Clinical evaluation of endovascular repair of abdominal aortic aneurysm based on long-term experiences.

Kulig¹,

Lewandowski²,

Rudel³

et al. 2020

Videosurgery and Other Miniinvasive Techniques

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Introduction The endovascular method as a less invasive treatment for patients with abdominal aortic aneurysm (AAA) has become an alternative to conventional open surgery. Aim The objective of the present study was to analyse the outcomes of endovascular treatment of AAA patients in long-term observation. Material and methods A group of 236 AAA patients subjected to planned endovascular aneurysm repair (EVAR) between 2010 and 2015 was reviewed. Rates of mortality, surgical complications and re-interventions were collected in the separate time periods, i.e. up to 30 days after surgery, 30 days to 3 years, and from 3 to 5 years after surgery. Cumulative rates of these parameters were evaluated in the short-term (up to 30 days after surgery), medium-term (up to 3 years), and long-term (up to 5 years after surgery) perspective. Results The median age of patients was 75 years, and the most common comorbidities were arterial hypertension (54%) and ischaemic heart disease (52%). Cumulative short-, medium- and long-term mortality rates were 2.5%, 14.2% and 28.9%, respectively. Total rates of surgical complications in short-, medium- and long-term observation were 7.6%, 12.6% and 17.5%, respectively. The cumulative rate of re-interventions ranged from 4.2% to 11.4%. Conclusions In the consecutive time periods, the increase in the percentage of surgical complications and re-interventions increased gradually, in contrast to mortality, where the curve grew significantly, which is expected due to the aging and numerous comorbidities in the observed group of patients.

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Endovascular Aneurysm Repair or Open Aneurysm Repair for the Treatment of Abdominal Aortic Aneurysm – The Latest Update

Cited by 3 publications

References 37 publications

Diverse roles of macrophage polarization in aortic aneurysm: destruction and repair

Diverse roles of macrophage polarization in aortic aneurysm: destruction and repair

Prevalence of chronic diseases among residents of care and treatment institutions in Wrocław

Clinical evaluation of endovascular repair of abdominal aortic aneurysm based on long-term experiences.

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