Endotherapy versus surgery for early neoplasia in Barrett's esophagus: a meta-analysis

Wu, Jun; Pan, Ya-min; Wang, Tiantian; Gao, Dao‐jian; Hu, Bing

doi:10.1016/j.gie.2013.08.005

Cited by 76 publications

(55 citation statements)

References 35 publications

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“…2,[20][21][22] Considering that the risk of lymph node metastasis in T1a disease is similar to the mortality of esophagectomy even at high-volume centers, there is a strong argument for endoscopic treatment of HGD/ EEA. 4,[23][24][25] In our study, the rate of SMC found after ER was 9.2%. Thus, provided that the BE mucosa is carefully evaluated and focal abnormalities endoscopically removed, the majority of patients with HGD/EEA can be managed endoscopically.…”

Section: Discussionsupporting

confidence: 45%

Long-term outcomes of a primary complete endoscopic resection strategy for short-segment Barrett’s esophagus with high-grade dysplasia and/or early esophageal adenocarcinoma

Bahin

Jayanna

Hourigan

et al. 2016

Gastrointestinal Endoscopy

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Section: Discussionsupporting

confidence: 45%

Long-term outcomes of a primary complete endoscopic resection strategy for short-segment Barrett’s esophagus with high-grade dysplasia and/or early esophageal adenocarcinoma

Bahin

Jayanna

Hourigan

et al. 2016

Gastrointestinal Endoscopy

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“…42 Moreover, endoscopic therapy is associated with an increased risk of local tumour recurrence compared to surgery. 52 Thus, patients with superficial submucosal infiltration (T1b) oesophagectomy optimises the prognosis, while in patients unfit for surgery, endoscopic resection is a good alternative. The learning curve associated with these therapies indicates the need for centralisation.…”

Section: Curative Treatment Endoscopic Treatmentmentioning

confidence: 99%

Oesophageal cancer

et al. 2017

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SummaryOesophageal cancer is a clinically challenging disease requiring a multidisciplinary approach.The extensive treatment may be associated with serious limitations in health-related quality of life and yet still a poor prognosis. Recent decades have witnessed a gradual improvement in prognosis in many countries. Endoscopic procedures have increasingly been used in the treatment of premalignant and early oesophageal tumours. Neoadjuvant therapy with chemotherapy or chemoradiotherapy has supplemented surgery as standard treatment of locally advanced oesophageal cancer. Surgery has become more standardised and centralised. There are several therapeutic alternatives for palliative treatment. This review aims to provide insights into the current clinical management, on-going controversies and future needs in oesophageal cancer.3

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“…Several recent publications have documented this shift toward using endoscopic therapy compared with esophageal resection surgery. 29,30 In a 1998 survey of American gastroenterologists, 50% said they managed BE HGD patients with endoscopic surveillance compared with only 20% who performed some type of endoscopic therapy. However, most patients were ultimately referred for esophageal resection surgery (82%).…”

Section: Discussionmentioning

confidence: 99%