Endothelium Dysfunction Pathway and Carotid Intima-Media Thickness in Hypertensive Patients: Role of Nos3 (Rs2070744) and Gnb3 (Rs5443) Genes’ Polymorphisms
Abstract:Objective:The crucial function of endothelium’s regulatory mechanisms is to maintain the balance between Monoxide Nitrogen (NO) release and endothelium-derived contracting factors production. Therefore, it is prognostically important to clarify the endothelial function (EF) deterioration pathway through the early biomarkers of EF and carotid intima media thickness (IMT) changes depending on GNB3 (rs5443) and NOS3 (rs2070744) genes’ polymorphism in essential arterial hypertension (EAH).Design and method:One-hun… Show more
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