“…By sampling individual cell transcriptomes across NC-derived lineages, our study complements prior investigations of lineage relationships, morphogenetic behaviors, genetic requirements, and spatial and cell-type-specific gene expression profiles (Eom et al, 2015; Irion et al, 2016; Johnson et al, 1995; Kelsh et al, 2017; McMenamin et al, 2014; Parichy and Spiewak, 2015; Singh et al, 2016; Singh et al, 2014). Multipotent progenitors that give rise to adult melanophores, some xanthophores, and iridophores are established in the embryo and reside within peripheral nerves as development progresses (Budi et al, 2011; Budi et al, 2008; Camargo-Sosa et al, 2019; Dooley et al, 2013a; Singh et al, 2016). As the adult pattern forms, some of these cells migrate to the hypodermis where they differentiate and integrate into dark stripes or light interstripes.…”