“…Reactive oxygen species (ROS) are implicated in the pathophysiology of vascular diseases, including endothelial dysfunction in hypertension, stroke, atherosclerosis and diabetes mellitus arterial lesions [1,2,3,4,5,6]. Mitochondria-derived ROS are key signals for the initiation of cellular responses to stress and disease-related risk factors, including aging, hypercholesterolemia, hyperglycemia, smoking, infections and hypoxia [7].…”