Endosonography-guided real-time fine-needle aspiration biopsy

Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB): past, present, and future

“…However, this technique only allowed the needle to be displayed as a small echogenic dot, making the procedure technically difficult and risky. In 1994, Wiersema et al 12,13 and Chang et al 14 stressed the importance of the presence of an on-site cytopathologist during the procedure to assess whether or not a specimen was adequate or whether further puncture attempts were necessary. Giovannini et al 16 confirmed and extended these preliminary studies, and showed that EUS-FNAB was safe, with no significant complications.…”

“…Wegener et al 11 EUS-FNAB for mediastinal and left adrenal lesion Wiersema et al 12,13 and EUS-FNAB for various lesions with on-site cytopathologist Chang et al 14 1995 Chang et al 15 EUS-FNAB for ascites and pleural effusion Harada et al 17 Development of a new needle (histological biopsy needle) 1996…”

“…12,[39][40][41] The current technique uses a new needle system, in which the endoscopist is able to maintain the endoscope in the proper position and simultaneously advance the needle into the lesion, under endosonographic guidance. Using this newly developed echoendoscope and biopsy device, EUS-FNAB procedures are easier to perform, and sufficient materials can be obtained more readily.…”

Complications of endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) for pancreatic lesions

“…1 An endoscopic-ultrasound-guided fineneedle aspiration biopsy (EUS-FNAB) enables a tissue diagnosis to be made when a definitive diagnosis cannot be obtained with EUS alone. [2][3][4][5] Pancreatic mass lesions have been reported to be among the best indications for EUS-FNAB since it was developed. 6 The sensitivity, and specificity of EUS-FNAB for pancreatic neoplasms in different series are 64%-85%, and 90%-100%, respectively.…”

Percutaneous needle biopsy

“…It is likely that the ability of percutaneous biopsy to guide the needle directly through the periphery and into the central portion of a mass and to disperse and obtain tumor cells from throughout the mass improves the quality of the specimen for cytologic interpretation. The emergence of a new technique, endoscopic ultrasound-guided needle biopsy, may ultimately combine the strengths of both ERCP and percutaneous biopsy techniques [9][10][11][12]. This procedure combines the benefits of the geographic proximity of an endoscopically introduced ultrasound transducer to the site of suspected pathology, and the superior nature of needle biopsy to that of ductal brushings.…”