“…Furthermore, patients selected for purely endoscopic resection of meningiomas (a narrow base of attachment, limited bony involvement, an obvious arachnoid plane on preoperative MRI, and smaller tumor PEER-REVIEW REPORTS size) often have features for which standard skull base microsurgical resection techniques have demonstrable excellent long-term outcome. Notwithstanding, there are a number of potential advantages to endoscopic instrumentation, which include the ability to introduce the viewing instrument directly over the region of interest, including potential "blind spots" during endocranial approaches, sharper image and higher contrast afforded by digital endoscopes with 3-CCD (charged coupled device) sensors (12), and a natural endonasal corridor to the midline skull base without brain retraction. To aid with depth perception, three-dimensional endoscopes may be available soon.…”