Endoscopic variceal ligation compared with endoscopic injection sclerotherapy for treatment of esophageal variceal hemorrhage: A meta-analysis

Dai, Cong; Liu, Weixin; Jiang, Min; Sun, Mingjun

doi:10.3748/wjg.v21.i8.2534

Cited by 108 publications

(78 citation statements)

References 26 publications

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“…This underscores the safety of this procedure and agrees with the work of several investigators who demonstrated a higher safety profile of rubber band ligation over sclerotherapy [14][15][16]. The high safety profile in this study may not be unconnected with the fact that prophylactic banding was done in most cases even without bleeding in predominantly in-patients.…”

Section: Discussionsupporting

confidence: 91%

Endoscopic Variceal Band Ligation: A Safe Way to Treat Oesophageal Varices

Femi¹

2016

CMR

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Abstract:Bleeding from oesophageal varices is the most dreaded complication of chronic liver disease and is associated with high mortality. Endoscopic variceal ligation is one of the more recent effective treatment modalities. This study was aimed at evaluating our experience with endoscopic variceal ligation with a view to stressing the safety associated with the procedure. A prospective study of consecutive patients presenting to the Jos University Teaching Hospital and FOMAS hospital endoscopic units was conducted over a 6 year period. A total of 199 sessions of endoscopic sessions were carried out on 83 patients with different grades of varices. There were 68 males and 15 females (M:F = 4.5:1). The mean age of the study population was 48 +/-7.4 years with age range of 17 to 63 years. The number of sessions of banding required for variceal obliteration in this study varied from 43 (51.8%) who had 3 sessions of banding, 30 (36.1%) who had 2 sessions and 10 (12.0%) that had a single session of variceal band ligation. All patients were placed on Propanolol tablets. There were no recorded episodes of procedure related bleeding, significant re-bleeding, post-procedure retrosternal pain, stricture or ulceration in this study, attesting to the safety of endoscopic variceal ligation.

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Section: Discussionsupporting

confidence: 91%

Endoscopic Variceal Band Ligation: A Safe Way to Treat Oesophageal Varices

Femi¹

2016

CMR

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“…Table 1 summarises the benefits and risks of the therapeutic interventions used in the treatment of duodenal varices. [20][21][22][23][24][25] Our case exemplifies the difficulties of identifying the source of duodenal variceal bleeding. It took four OGDs to locate the source of bleeding and this was possible because of active bleeding at the time of the fourth OGD.…”

Section: Discussionmentioning

confidence: 75%

Duodenal variceal bleed: an unusual cause of upper gastrointestinal bleed and a difficult diagnosis to make

Bhagani

Winters

Moreea³

2017

BMJ Case Reports

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We present a case of recurrent upper gastrointestinal (GI) bleeding in a man aged 57 years with primary biliary cholangitis who was ultimately diagnosed with an isolated duodenal variceal bleed, which was successfully treated with histoacryl glue injection. Duodenal varices are an uncommon presentation of portal hypertension and can result in significant GI bleeding with a high mortality. Diagnosis can be difficult and therapeutic options limited. Endoscopic variceal sclerotherapy with histoacryl glue provides an effective treatment, though endoscopists need to remain aware of and vigilant for the serious complications of this treatment option.

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“…Currently, endoscopic therapy via the obliteration of varices is the first choice of treatment to control variceal bleeding . In China, the two main therapeutic endoscopic modalities that are commonly applied in clinical setting are endoscopic variceal sclerotherapy (EVS) and endoscopic variceal ligation (EVL) . For EVS, a sclerosing agent is injected into the varices to induce vessel thrombosis, which subsequently leads to variceal obliteration .…”

Section: Introductionmentioning

confidence: 99%

“…3 In China, the two main therapeutic endoscopic modalities that are commonly applied in clinical setting are endoscopic variceal sclerotherapy (EVS) and endoscopic variceal ligation (EVL). 4 For EVS, a sclerosing agent is injected into the varices to induce vessel thrombosis, which subsequently leads to variceal obliteration. 5 EVS is effective and relatively inexpensive, and can be easily carried out after training.…”

Section: Introductionmentioning

confidence: 99%

Reasons and risk factors for irregular‐interval endoscopic variceal sclerotherapy in patients with esophageal variceal bleeding

Shi

Guo

et al. 2016

J of Digest Diseases

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Early rebleeding, initial emergency treatment, and treatment over holidays may necessitate irregular sclerotherapy intervals in patients with EVB. Moreover, ascites, variceal erosion, and maximum injected volume of sclerosing agent per session are risk factors for emergency sclerotherapy, whereas elective adjustments to treatment schedules as a result of holidays do not affect the outcomes of patients undergoing EVS for EVB.

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Endoscopic variceal ligation compared with endoscopic injection sclerotherapy for treatment of esophageal variceal hemorrhage: A meta-analysis

Abstract: Our meta-analysis has found that EVL is better than EIS in terms of the lower rates of rebleeding, complications, and the higher rate of variceal eradication. Therefore, EVL is the first choice for esophageal variceal bleeding.

Cited by 108 publications

References 26 publications

Endoscopic Variceal Band Ligation: A Safe Way to Treat Oesophageal Varices

Endoscopic Variceal Band Ligation: A Safe Way to Treat Oesophageal Varices

Duodenal variceal bleed: an unusual cause of upper gastrointestinal bleed and a difficult diagnosis to make

Reasons and risk factors for irregular‐interval endoscopic variceal sclerotherapy in patients with esophageal variceal bleeding

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