Endoscopic ultrasound in restaging of esophageal cancer after neoadjuvant chemoradiation

Isenberg, Gerard; Chak, Amitabh; Canto, Marcia I.; Levitan, Nathan; Clayman, Julie; Pollack, Bonnie J.; Sivak, Michael

doi:10.1016/s0016-5107(98)70157-9

Cited by 147 publications

(75 citation statements)

References 14 publications

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“…Isenberg et al concluded that EUS after CRT was not accurate when using the TNM classification system but found that, if the maximal cross-sectional area was measured and followed, then this proved to be more useful. 19 A response to therapy was defined as a reduction of cross-sectional area by 50%, and this was validated by Chak and colleagues, who also showed a survival benefit for patients who achieved this level of response. 16,18,20 Bowrey et al evaluated a similar group of patients and found the same inaccuracies and unreliability of EUS for restaging esophageal carcinoma after CRT that we found.…”

Section: Discussionmentioning

confidence: 99%

The accuracy of endoscopic ultrasound for restaging esophageal carcinoma after chemoradiation therapy

Kalha

Kaw

Fukami

et al. 2004

Cancer

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The study of fault detection and diagnosis of electrical machines, in particular induction motors, as well as the teaching of their behavior requires practical experience in this field. To provide this experience to the students this paper presents an experimental system that can be used with a standard industrial electrical induction machine. This system is based on only one healthy induction machine that is operated under faulty operating modes. Several fault types such as stator winding faults, bearing faults, or broken bars can be tested. The developed system also allows testing the behavior of the electrical machine for different load types. Several typical loads in which the torque depends of time or speed were implemented. The system is based on computer equipment with a DSPIC, a testing system and an induction machine. © 2010 Wiley Periodicals, Inc. Comput Appl Eng Educ 20: 611–618, 2012

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Section: Discussionmentioning

confidence: 99%

The accuracy of endoscopic ultrasound for restaging esophageal carcinoma after chemoradiation therapy

Kalha

Kaw

Fukami

et al. 2004

Cancer

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“…EUS is unable to reliably determine tumour depth following neoadjuvant treatment [15,16,[18][19][20]. EUS is an invasive procedure with a 20-50% chance of the probe unable to be manoeuvred through the stenotic segment.…”

Section: Introductionmentioning

confidence: 99%

“…A recent systematic review has shown that EUS and CT have poor sensitivity in identifying disease response in oesophageal carcinoma, 50-100% and 33-55% respectively [21] CT and EUS imaging techniques are often insensitive, relying on changes in tumour bulk which may take considerable time to become apparent. Furthermore, these modalities may have difficulty in distinguishing residual tumour, necrosis, scar tissue and oedema [10,11,15,16,19,20]. Positron Emission Tomography (PET) images metabolic activity via the distribution of positron emitting tracers that are incorporated into metabolic processes.…”

Section: Introductionmentioning

confidence: 99%

Positron emission tomography for monitoring response to neoadjuvant therapy in patients with oesophageal and gastro-oesophageal junction carcinoma

Suttie

Welch

Park

2009

European Journal of Surgical Oncology (EJSO)

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Statement of Expertise:This group has published on PET work in conjunction with oesophago-gastric cancers. Stuart Suttie has undertaken a period of research, culminating in a higher degree, based on PET imaging ( 18 FDG and 11 C-choline for predicting response to chemotherapy in oesophageal cancer MethodsAn electronic search was performed of Pubmed, Ovid and Embase websites to identify studies, in English language, using the search terms: PET; oesophageal;oesophago-gastric; survival; cancer; response; chemotherapy and chemoradiotherapy.The reference lists were searched manually to identify further relevant studies. ResultsTwenty two studies were identified, all using 18 FDG as the tracer, using PET to predict response in terms of pathological response and survival following neoadjuvant therapy (chemotherapy/chemoradiotherapy). PET had a varying degree of success in predicting both pathological response and survival outcomes, with only one study using PET to influence management decisions. ConclusionsPET seems a promising technique, but large scale conclusions are hindered by small study numbers, lack of criteria as to what constitutes a response and markedly differing PET imaging times. A large randomised trial, concerning a homogeneous group of patients and tumours is required before using PET to influence management.

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“…Endoskopik ultrasonografi neoadjuvan tedavi sonrası yeniden evrelemede ilk evrelemedeki kadar başarılı (50)(51)(52). Kemotrapi ve radyoterapiye bağlı gelişen inflamasyonu ve fibrozis rezidü tümörden ayırt edilemeyebilir veya rezidü tümör yanlışlıkla olduğundan büyük görülebilir (53).…”

Section: Preoperatif Neoadjuvan Tedaviye Yanıtın Değerlendirilmesiunclassified

Radiology of Esophageal Cancer

Uzun¹

2013

Toraks Cer Bult

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Endoscopic ultrasound in restaging of esophageal cancer after neoadjuvant chemoradiation

Cited by 147 publications

References 14 publications

The accuracy of endoscopic ultrasound for restaging esophageal carcinoma after chemoradiation therapy

The accuracy of endoscopic ultrasound for restaging esophageal carcinoma after chemoradiation therapy

Positron emission tomography for monitoring response to neoadjuvant therapy in patients with oesophageal and gastro-oesophageal junction carcinoma

Radiology of Esophageal Cancer

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