“…Therefore, the use of EUS in tissue acquisition for the diagnosis of splenic lesions has increased during recent years. In a recent systematic review and meta-analysis, the authors reported an EUS-guided tissue acquisition diagnostic specificity of 77% and sensitivity of 85%, with no major complications [ 78 ]. In another meta-analysis, Lisotti et al demonstrated a diagnostic accuracy of 93% and overall accuracy of 88% for tissue acquisition using EUS-FNA in all the articles reviewed.…”