Endoscopic Ultrasound-Guided Pancreatic Duct Aspiration: Diagnostic Yield and Safety

Lai, Rebecca; Stanley, Michael W.; Bardales, Ricardo H.; Linzie, Bradley M.; Mallery, Shawn

doi:10.1055/s-2002-33443

Cited by 67 publications

(51 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[32][33][34][35][36][37][38] The presence of mitoses in EUS-FNA specimens of GISTs appears to be associated with malignancy. 19 However, EUS-FNA is associated with several limitations.…”

Section: Discussionmentioning

confidence: 99%

Estimation of malignant potential of GI stromal tumors by contrast-enhanced harmonic EUS (with videos)

Sakamoto

Kitano

Matsui

et al. 2011

Gastrointestinal Endoscopy

107

View full text Add to dashboard Cite

“…[32][33][34][35][36][37][38] The presence of mitoses in EUS-FNA specimens of GISTs appears to be associated with malignancy. 19 However, EUS-FNA is associated with several limitations.…”

Section: Discussionmentioning

confidence: 99%

Estimation of malignant potential of GI stromal tumors by contrast-enhanced harmonic EUS (with videos)

Sakamoto

Kitano

Matsui

et al. 2011

Gastrointestinal Endoscopy

107

View full text Add to dashboard Cite

“…All EUS-FNA procedures were performed with a linear echoendoscope (GF-UCT240P-AL5; Olympus, Center Valley, Pa., USA) using either a 22-gauge Endocoil (Wilson-Cook, Winston-Salem, N.C., USA) or a 25-gauge Echotip (Wilson-Cook) needle. The technique of EUS-FNA is well established [1,2,16,17,18]. In brief, a needle was advanced into the lesion under EUS visualization.…”

Section: Methodsmentioning

confidence: 99%

A Prospective Comparison of Liquid-Based Cytology and Traditional Smear Cytology in Pancreatic Endoscopic Ultrasound-Guided Fine Needle Aspiration

Lee

Choi²,

Jang³

et al. 2011

Acta Cytologica

View full text Add to dashboard Cite

Objective: To compare results of liquid-based cytology (LBC) and the conventional smear method (SMEAR) when performing endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for lesions of suspected pancreatic malignancy without an on-site cytopathologist. Study Design: Fifty-eight patients were prospectively enrolled between July and December 2009. Aspirates obtained from the first needle pass were randomized either to SMEAR or LBC. Another sample from the second needle pass was allocated to the other method. The rest of the aspirates from the third or later needle passes were used for SMEAR. Diagnostic accuracy was compared and related factors were pursued. Results: Although both methods were 100% specific, LBC was inferior to SMEAR in terms of sensitivity, negative predictive value, and accuracy. However, LBC provided correct diagnoses in 2 out of 3 cases of false negatives for malignancy by SMEAR in which blood was highly contaminated. Although no factor was identified for LBC, low blood contamination and more than 3 needle passes were related with accurate diagnosis in SMEAR. Conclusion: LBC was less accurate than SMEAR when performing pancreatic EUS-FNA without an on-site cytopathologist. However, LBC might serve as a good complement to SMEAR if blood contamination is profound.

show abstract

“…Color flow and Doppler sonography was performed to exclude intervening vascular structures and to select a vessel-free needle track to avoid vessel puncture. EuS-FNA was performed as previously described (17). Briefly, after advancing the needle into the lesion under EuS visualization, the central stylet was removed, a 10-ml syringe with extension tubing was attached to the hub of the needle, and suction was applied as the needle was moved backward and forward within the lesion.…”

Section: Methodsmentioning

confidence: 99%

Analysis of the amount of tissue sample necessary for mitotic count and Ki-67 index in gastrointestinal stromal tumor sampling

et al. 2014

View full text Add to dashboard Cite

Abstract. There are no established opinions concerning whether the amount of tissue affects the accuracy of histological analyses in gastrointestinal stromal tumors (GISTs). The aim of the present study was to investigate the appropriate amount of tissue sample needed for mitotic count based on the risk classification of GISTs and the Ki-67 index using the following three methods: endoscopic ultrasound-guided fine-needle aspiration (FNA), a novel sampling method called tunneling bloc biopsy (TBB), and biopsy forceps followed by TBB (Bf). Forty-three samples (12 FNA, 17 TBB and 14 Bf) diagnosed as GISTs by immunohistological analysis were utilized. The major and minor axes and overlay area of one piece of specimen (OPS) from the three sampling methods were measured using digital imaging software and were analyzed comparatively regarding the acquisition of histological data. The mean major and minor axes (mm) and overlay areas (mm 2 ) were in the order of TBB > Bf > FNA. The evaluable rates by mitotic count and Ki-67 were, respectively, 75% (9/12) and 83.3% (10/12) for FNA samples, 100% (17/17) and 100% (17/17) for TBB samples, and 100% (14/14) and 100% (14/14) for Bf samples (P>0.05). Three FNA samples were judged unevaluable due to too small specimens in overall diagnosis including mitotic count and Ki-67, calculating the cut-off value for the overlay area of OPS as 0.17 mm 2 . Comparing the concordance rates between the pre-and post-operative samples, TBB samples was significantly better than FNA (P<0.05). Conclusively, while the amounts of tissues obtained by TBB and Bf are unnecessary for the histological assessment of mitotic count and Ki-67 index, developments of the FNA method are needed to minimize sample error. Considering the technical aspects, as well as the size of the specimens, could help to guide therapeutic planning and improve diagnostic yield for GI subepithelial tumors.

show abstract

Endoscopic Ultrasound-Guided Pancreatic Duct Aspiration: Diagnostic Yield and Safety

Abstract: This preliminary experience suggests that EUS-guided pancreatic duct aspiration is safe and can provide diagnostic material in a significant number of patients with unexplained pancreatic duct dilation.

Cited by 67 publications

References 12 publications

Estimation of malignant potential of GI stromal tumors by contrast-enhanced harmonic EUS (with videos)

Estimation of malignant potential of GI stromal tumors by contrast-enhanced harmonic EUS (with videos)

A Prospective Comparison of Liquid-Based Cytology and Traditional Smear Cytology in Pancreatic Endoscopic Ultrasound-Guided Fine Needle Aspiration

Analysis of the amount of tissue sample necessary for mitotic count and Ki-67 index in gastrointestinal stromal tumor sampling

Contact Info

Product

Resources

About