Endoscopic ultrasound-guided gallbladder drainage after real-time assessment of cystic duct exclusion following biliary placement of an uncovered metal

EUS-guided gallbladder drainage and subsequent peroral endoscopic cholecystolithotomy: A tool to reduce chemotherapy discontinuation in neoplastic patients?

“…POEC-CL has been explored in an initial proof-of-concept series of 5 to 25 cases, with a very high rate of technical success (88%-100%) and a low rate of adverse events (0%-3.84%). [6][7][8][9][10][11] This possibility pushes EUS-GBD beyond AC palliation in patients unfit for surgery, offering a potentially "curative" option in all patients in whom surgery is undesirable.…”

“…In this scenario, AC might be an expected adverse event of local cancer invasion or palliative procedures (eg, SEMS placement). 7,8 An eventual surgical treatment can expose these patients to a discontinuation or delay in chemotherapy that could significantly affect their prognosis. In another elderly, frail, and comorbid patient with a severe form of myeloprolierative disease, the procedure resulted in a dramatic improvement of severe septic shock.…”