Endoscopic Ultrasound-Guided Ablation of Liver Tumors

Chua, Tiffany; Faigel, Douglas O.

doi:10.1016/j.giec.2018.11.007

Cited by 18 publications

(16 citation statements)

References 39 publications

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“…A thrilling offshoot of EUS guided therapeutic interventions has been EUS guided local treatment of tumor lesions (both pancreatic and hepatic tumors)[ 80 ]. EUS-guided tumor management is a new experimental application that has shown promise in reaching difficult lesions (left lobe, caudate lobe), provided a rescue option in refractory cases, and has potential to improve quality of life by minimizing systemic side effects[ 81 , 82 ]. This procedure has been extensively studied in cases of pancreatic neoplasm, but its role in hepatic tumors (primary or metastatic) is still in its infancy.…”

Section: Eus For Liver Parenchyma Associated Diseasesmentioning

confidence: 99%

Role of endoscopic ultrasound in the field of hepatology: Recent advances and future trends

Dhar¹,

Samanta²

2021

WJH

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The role of endoscopic ultrasound (EUS) as a diagnostic and therapeutic modality for the management of various gastrointestinal diseases has been expanding. The imaging or intervention for various liver diseases has primarily been the domain of radiologists. With the advances in EUS, the domain of endosonologists is rapidly expanding in the field of hepatology. The ability to combine endoscopy and sonography in one hybrid device is a unique property of EUS, together with the ability to bring its probe/transducer near the liver, the area of interest. Its excellent spatial resolution and ability to provide real-time images coupled with several enhancement techniques, such as contrast-enhanced (CE) EUS, have facilitated the growth of EUS. The concept of “Endo-hepatology” encompasses the wide range of diagnostic and therapeutic procedures that are now gradually becoming feasible for managing various liver diseases. Diagnostic advancements can enable a wide array of techniques from elastography and liver biopsy for liver parenchymal diseases, to CE-EUS for focal liver lesions to portal pressure measurements for managing various liver conditions. Similarly, therapeutic advancements range from EUS-guided eradication of varices, drainage of bilomas and abscesses to various EUS-guided modalities of liver tumor management. We provide a comprehensive review of all the different diagnostic and therapeutic EUS modalities available for the management of various liver diseases. A synopsis of all the technical details involving each procedure and the available data has been tabulated, and the future trends in this area have been highlighted.

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Section: Eus For Liver Parenchyma Associated Diseasesmentioning

confidence: 99%

Role of endoscopic ultrasound in the field of hepatology: Recent advances and future trends

Dhar¹,

Samanta²

2021

WJH

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“…HIFU itself has been utilized as a thermal ablation for ablation of liver metastases through surgical or transcutaneous routes [ 7 ]. Compared to percutaneous approaches, the application of EUS in RFA is more beneficial, especially in anatomical locations, which are difficult to be visualized and/or reached [ 47 ].…”

Section: The Therapeutic Role Of Endoscopic Ultrasoundmentioning

confidence: 99%

The Role of Interventional Endoscopic Ultrasound in Liver Diseases: What Have We Learnt?

Lesmana

Paramitha

Gani

2021

Canadian Journal of Gastroenterology and Hepatology

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Chronic liver disease (CLD) is still a major problem, where the disease progression will lead to liver cirrhosis (LC) or hepatocellular carcinoma (HCC). Portal hypertension (PH) management and loco-regional therapy for HCC have become the cornerstones in advanced liver disease management. Recently, there are studies looking at the potential role of interventional endoscopic ultrasound (EUS) in liver diseases. EUS may be useful in vascular changes of the digestive wall evaluation, performing dynamic assessment of hemodynamic changes, predicting variceal bleeding and rebleeding risk, and assessing the pharmacological effects. In PH management, EUS-guided vascular therapy—which revolves around glue injection, endovascular coil placement/embolization, and combination of both—has shown promising results. As a diagnostic modality for liver cancer, the implementation of EUS in liver diseases is currently not only limited to liver biopsy (EUS-LB) but also in shear-wave elastography (SWE) and portal pressure gradient measurement, as well as portal vein sampling. The application of EUS-guided radiofrequency ablation (EUS-RFA) and tumor injection can also overcome the limitations shown by both modalities without EUS. Nevertheless, establishing EUS as a firm diagnostic and therapeutic modality is still challenging since the performance of interventional EUS requires high expertise and adequate facilities.

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“…Various ablative techniques are available for focal liver lesions such as fine-needle injection using alcohol (FNI), radiofrequency ablation (RFA), photodynamic therapy (PDT), and cryoablation (CYA). [ 120 ] EUS-guided FNI using ethanol has been used in cystic lesions in the liver. Nakaji et al .…”

Section: Eus-guided Ablation Of Liver Tumorsmentioning

confidence: 99%

Diagnostic and interventional EUS in hepatology: An updated review

2022

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EUS has become an increasingly used diagnostic and therapeutic modality in the armamentarium of endoscopists. With ever-expanding indications, EUS is being used in patients with liver disease, for both diagnosis and therapy. EUS is playing an important role in providing additional important information to that provided by cross-sectional imaging modalities such as computerized tomography and magnetic resonance imaging. Domains of therapy that were largely restricted to interventional radiologists have become accessible to endosonologists. From liver biopsy and sampling of liver lesions to ablative therapy for liver lesions and vascular interventions for varices, there is increased use of EUS in patients with liver disease. In this review, we discuss the various diagnostic and therapeutic applications of EUS in patients with various liver diseases.

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Endoscopic Ultrasound-Guided Ablation of Liver Tumors

Cited by 18 publications

References 39 publications

Role of endoscopic ultrasound in the field of hepatology: Recent advances and future trends

Role of endoscopic ultrasound in the field of hepatology: Recent advances and future trends

The Role of Interventional Endoscopic Ultrasound in Liver Diseases: What Have We Learnt?

Diagnostic and interventional EUS in hepatology: An updated review

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