Endoscopic ultrasound elastography for small solid pancreatic lesions with or without main pancreatic duct dilatation

Kataoka, Kunio; Ishikawa, Takuya; Ohno, Eizaburo; Iida, Tadashi; Suzuki, Hirotaka; Uetsuki, Kota; Nakamura, Masanao; Honda, Takashi; Ishigami, Masatoshi; Kawashima, Hiroki; Hirooka, Yoshiki; Fujishiro, Mitsuhiro

doi:10.1016/j.pan.2020.12.012

Cited by 15 publications

(10 citation statements)

References 40 publications

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“…Für die Differenzierung zwischen benignen und malignen Pankreasraumforderungen kann die EUS-Elastografie hilfreich sein. Zum einen weist die EUS-Elastografie eine sehr gute Sensitivität auf und zum anderen hat sie einen hohen negativen Prädiktionswert [66,67]. Die PK-Verdachtsdiagnose weiter erhärten kann schließlich die Kontrastmittelgabe (CE-EUS) [68].…”

Section: Endosonografie Und Pk-früherkennungunclassified

Früherkennung des sporadischen Pankreasadenokarzinoms

Scherübl

2023

Z Gastroenterol

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ZusammenfassungDas Pankreasadenokarzinom (PK) nimmt stetig an Häufigkeit zu und stellt bereits die dritthäufigste tumorbedingte Todesursache in Deutschland dar. Voraussichtlich rückt es bis 2030 auf den 2. Platz und bis 2050 gar auf den 1. Platz der krebsbedingten Todesfälle vor. Das Pankreaskarzinom wird generell spät diagnostiziert und die 5-Jahre-Überlebensrate liegt bei nur 10%. Wird das PK aber im Tumorstadium IA diagnostiziert und therapiert, so beträgt das 5-Jahresüberleben rund 80%. Früherkennungsinitiativen verfolgen deshalb das Ziel, Hochrisikopersonen zu identifizieren und das sporadische Pankreaskarzinom frühzeitig festzustellen. Personen über 50 mit neu diagnostiziertem Diabetes stehen dabei im Mittelpunkt des Interesses. Aktuelle Entwicklungen und Früherkennungsstrategien werden angesprochen.

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Section: Endosonografie Und Pk-früherkennungunclassified

Früherkennung des sporadischen Pankreasadenokarzinoms

Scherübl

2023

Z Gastroenterol

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“…The technique does not increase operation time or risk of adverse effects on evaluation [78]. Endoscopic ultrasound elastography has also been used in the identification of pancreatic duct dilatation that correlated with higher stiffness index and head-based locations in patients with pancreatic cancer [77]. The elastic modulus as shown by elastography is also useful in appendicitis and other infections.…”

Section: Use In Gastrointestinal Tissuesmentioning

confidence: 99%

Associations of Real-Time Ultrasound and Strain and Shear Wave Elastography with Gastrointestinal Organs: A Systematic Review

Javed,

Ghazanfar,

Jyala

et al. 2023

Diagnostics

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Ultrasound elastography is gaining attention for its diagnostic potential across various medical fields, and its physical properties make it valuable in modern clinical medicine. However, its specific attributes, especially in the context of recent medical advancements, remain relatively unexplored. This study aimed to identify instrument-specific characteristics and applications of real-time ultrasound elastography, shear wave elastography, and strain elastography, particularly within gastroenterology. Following PRISMA guidelines, the study examined elastography articles on databases like PubMed, resulting in 78 included articles. Data on patient demographics, organ involvement, specificity, sensitivity, accuracy, positive predictive value, and negative predictive value were extracted. Statistical analysis involved SPSS version 21, with significance set at p < 0.05. The majority of patients were male (50.50%), with a mean age of 42.73 ± 4.41 years. Shear wave elastography was the most prevalent technique (48.7%), and liver investigations were predominant in gastroenterology (34.6%). Gastrointestinal applications showed higher sensitivity, positive predictive value, and negative predictive values (p < 0.05) but lower specificity (p < 0.05). Real-time ultrasound elastography exhibited increased specificity, accuracy, and predictive values (p < 0.05). Ultrasound elastography appears more accurate and effective in gastroenterological settings. Nonetheless, its performance depends on instrument-specific and operator-dependent factors. While promising, further studies are necessary to ascertain optimal utilization in both gastrointestinal and non-gastrointestinal conditions.

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“…Currently, there are seven meta-analyses (Table 1) [31][32][33][34][35][36][37] that include strain EUS-E for pancreatic cancer and showed a specificity of 92-98% and a specificity of 67-76%. However, two studies assessed small pancreatic tumors of less than 15 and 20 mm, respectively, and pointed out that EUS-E might be confident in suggesting that PDAC is a stiff tumor [38,39]. Kataoka et al [38] analyzed 126 cases of small pancreatic lesions associated or not with main pancreatic duct dilation.…”

Section: Pancreatic Massesmentioning

confidence: 99%

“…However, two studies assessed small pancreatic tumors of less than 15 and 20 mm, respectively, and pointed out that EUS-E might be confident in suggesting that PDAC is a stiff tumor [38,39]. Kataoka et al [38] analyzed 126 cases of small pancreatic lesions associated or not with main pancreatic duct dilation. They concluded that a stiffness ratio was definitely higher for pancreatic cancer 62:3 vs. 29:32, P < 0.001.…”

Section: Pancreatic Massesmentioning

confidence: 99%

Endoscopic Ultrasound Elastography: New Advancement in Pancreatic Diseases

Ungureanu¹,

Săftoiu²

2022

Elastography - Applications in Clinical Medicine

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Elastography opened up new frontiers for pancreatic disease, as it may aid in tumor mass differentiation. Ultrasound strain elastography and ultrasound shear-wave elastography have been used so far by transabdominal transducers. New technological advancements have embedded elastography techniques in endoscopic ultrasound (EUS), thus enabling a better evaluation of patients with pancreatic tumors, chronic pancreatitis, autoimmune pancreatitis, gastrointestinal subepithelial lesions, and lymph node involvement. Moreover, EUS-E might help in guiding EUS-Fine Needle Aspiration or EUS-Fine Needle Biopsy when addressing solid pancreatic tumors, for proper tissue harvesting. Furthermore, artificial intelligence methods may bypass the human factor and lead to better diagnostic results.

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Endoscopic ultrasound elastography for small solid pancreatic lesions with or without main pancreatic duct dilatation

Cited by 15 publications

References 40 publications

Früherkennung des sporadischen Pankreasadenokarzinoms

Früherkennung des sporadischen Pankreasadenokarzinoms

Associations of Real-Time Ultrasound and Strain and Shear Wave Elastography with Gastrointestinal Organs: A Systematic Review

Endoscopic Ultrasound Elastography: New Advancement in Pancreatic Diseases

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