Endoscopic treatment of pancreatic ascites

Kozarek, Richard A.; Jiranek, Geoffrey C.; Traverso, L. William

doi:10.1016/s0002-9610(05)80190-4

Cited by 71 publications

(28 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The study population is large lecular and cellular biology have generated a better understanding of the disease [1,[61][62][63][64][65]. Histologically, it is (n>302) and the severity of acute pancreatitis adequate, given the overall mortality rate of 16% (43/302) and the characterized by a progressive inflammatory process with irreversible pathological changes leading to both exocrine tion have been investigated in several studies [79][80][81][82][83][84][85][86][87][88][89][90][91][92][93][94][95]. Both drugs appear to be effective in some cases (table 2).…”

mentioning

confidence: 99%

The Role of Octreotide and Somatostatin in Acute and Chronic Pancreatitis

et al. 1999

View full text Add to dashboard Cite

Acute pancreatitis may follow a mild or a severe course. Whereas mild or edematous pancreatitis is a self-limiting disease with a low complication rate and low death rate, morbidity and mortality in severe or necrotizing pancreatitis are still unacceptably high. The major problem is the lack of a specific drug, especially in the early phase of the disease, to interfere with the systemic inflammatory response syndrome and to limit or prevent complications of the disease. Although the initiating pathophysiological process is not known, the destruction of the gland (‘autodigestion’) by digestive enzymes may be responsible for disease progression. Inhibition of pancreatic activity, which reduces exocrine secretion and further prevents the release and activation of enzymes, was therefore suggested as a specific treatment concept. The results of clinical investigations using somatostatin or its analogue are controversial, since all these trials had low statistical power. In a recent multicenter randomized controlled study with a large number of patients (n = 302) (and an adequate level of disease severity), no benefit of octreotide on progression or outcome was found. Chronic pancreatitis is characterized by an irreversible destruction of the exocrine and endocrine pancreatic parenchyma leading to maldigestion and diabetes. Pain, which may be caused by increased ductal pressure, is one of the most dominant symptoms in chronic pancreatitis. However, no beneficial effects on pain with pancreatic exocrine secretion-inhibiting drugs have been demonstrated. Treatment of other complications of the disease (pseudocyst formation, fistula and pancreatic ascites), with somatostatin or octreotide has given conflicting results. However, in a prophylactic clinical setting (e.g. elective pancreatic surgery) the inhibition of exocrine pancreatic secretion reduces complications.

show abstract

mentioning

confidence: 99%

The Role of Octreotide and Somatostatin in Acute and Chronic Pancreatitis

et al. 1999

View full text Add to dashboard Cite

show abstract

“…There are reports of post-traumatic pancreatic ascites, in which the pancreatic tail was sheared off after trauma such as vehicle collisions or sports injury. [4] However, patients typically have a history of chronic alcoholism, pancreatic disease, and liver disease. Pleural effusions may or may not be present, and pancreatic ascites is more common in males.…”

Section: Discussionmentioning

confidence: 99%

Black Ascites: An interesting presentation of pancreatic duct leak

Ascha

Hanouneh

2016

CRIM

View full text Add to dashboard Cite

Introduction: Common causes of ascites include liver cirrhosis, heart failure, and malignancy. Pancreatic etiology is less common for ascites, but is most often a result of chronic pancreatitis secondary to alcoholic liver damage or pancreatic duct leak. Case description: The following case describes a patient with black-colored ascites secondary to pancreatic duct leak after total colectomy with ileorectal anastomosis. The colectomy was indicated by MYH-positive polyposis, and the there was no known prior liver or pancreas disease. Management included pancreatic duct stent placement, and drains from the pancreatic tail. Discussion: Pancreatic etiology is rare among ascites diagnoses; this case is even rarer due to gross appearance of the ascitic fluid and its iatrogenic cause.

show abstract

“…It is reasonable to perform stenting of the stenotic portion of the pancreatic duct for the treatment of pancreatic juice leakage with the pancreatic duct stenosis [11,12]. Furthermore, suction of the pancreaticjuice from the distal portion of the pancreatic duct is more effective for the treatment of these patients.…”

Section: Discussionmentioning

confidence: 99%

External Pancreatic Juice Drainage Through a Percutaneous Endoscopic Drainage Tube for the Patient With a Postoperative Pancreatic Juice Leakage

Nishiguchi

Nishino

Yoshikawa

et al. 1998

Diagnostic and Therapeutic Endoscopy

View full text Add to dashboard Cite

Percutaneous endoscopic gastrostomy (PEG) has been widely accepted for patients who have no swallowing ability but have an intact gut. Its clinical application is mainly for nutritional support and decompression ofthe intestine in patients with bowel obstruction. In this paper, we report external pancreatic juice drainage through a percutaneous endoscopic drainage tube in a patient with postoperative pancreatic juice leakage. Soon after this procedure, pancreatic juice leakage subsided. This procedure was minimally invasive for the patient and may be a new application ofPEG to maintain the good quality oflife (QOL) in a patient with pancreatic juice leakage.

show abstract

Endoscopic treatment of pancreatic ascites

Cited by 71 publications

References 19 publications

The Role of Octreotide and Somatostatin in Acute and Chronic Pancreatitis

The Role of Octreotide and Somatostatin in Acute and Chronic Pancreatitis

Black Ascites: An interesting presentation of pancreatic duct leak

External Pancreatic Juice Drainage Through a Percutaneous Endoscopic Drainage Tube for the Patient With a Postoperative Pancreatic Juice Leakage

Contact Info

Product

Resources

About