Endoscopic third ventriculostomy and cerebrospinal fluid shunting for pure communicating hydrocephalus in children

Usami, Kenichi; Ishisaka, Eitaro; Ogiwara, Hideki

doi:10.1007/s00381-021-05242-4

Cited by 6 publications

(4 citation statements)

References 28 publications

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“…Communication with ETV action, either with or without CPC, fails in cases of hydrocephalus, possibly due to failure to achieve differences in pulsative pressure or because CSF absorption function in the intraventricular glymphatic system is lost due to bleeding or infection. [15] There were several causes of hydrocephalus in this study, according to Holwerda et al, intracranial bleeding (42% of cases) and congenital abnormalities (22% of cases) were the most common etiologies. The average operation is performed at the age of 1-6 months, and for the interventions performed, 50% of them have to re-operate, but it is not clear what revision of the intervention was carried out.…”

Section: Discussionmentioning

confidence: 54%

A Selection of Surgical Interventions in Pediatric Hydrocephalus

Musfirah

Iskandar

2023

AANHS-J

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Introduction: Hydrocephalus is a condition in which the flow of cerebrospinal fluid is disturbed due to an imbalance between production and reabsorption or because there are obstacles along its distribution channel. The most common surgical intervention and standard strategy for treating hydrocephalus in recent years has been the placement of a shunt, particularly a ventriculoperitoneal shunt (VP-Shunt). In addition to shunt placement, endoscopic third ventriculostomy (ETV) and choroid plexus coagulation (CPC) are currently being performed simultaneously, considering that the combination of the two procedures is sufficient to provide maximum results and can even reduce the risk of failure. Method: The method of literature review is used in this study.The method chosen is preferred reporting items for systematic reviews and meta-analyses (PRISMA), which involves selecting the characteristics of literature through electronic media with database searches through the PubMed and Google Scholar sites. Patients diagnosed with hydrocephalus, both communicative and noncommunicative, with an age of 18 years; surgical intervention with a Vp-shunt; EVT with or without CPC; and a 3-month follow-up were the inclusion criteria. Result: There were 1,251 samples included in the 10 articles in this study, 7 of these articles had samples with non-communicable hydrocephalus, with the most common etiologies being post-infection and hemorrhage. The selected interventions, both Vp-Shunt and ETV with or without CPC, have a high percentage of success rates, with an average age of intervention in this study of 6 months. Conclusion: The choice of intervention in cases of hydrocephalus should be based on patient characteristics. Installation of a shunt, ETV, or ETV/CPC may et he first choice based on the etiology of the hydrocephalus, the patient’s age, and a risk assessment that takes into account the complications that may arise from the selected procedure

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Section: Discussionmentioning

confidence: 54%

A Selection of Surgical Interventions in Pediatric Hydrocephalus

Musfirah

Iskandar

2023

AANHS-J

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“…It is recommended for young children receiving a loading dose of levetiracetam (20 mg/kg) at the start of surgery and a maintenance dose (10 mg/kg twice per one day) for the following 7 days [8]. In a previous study, a patient's age was found as an in uential factor of the success rate of ETV, and younger patients tended to undergo additional surgery after failure of ETV [4]. As the reduction of postoperative serum potassium and calcium levels was found as a risk factor for epilepsy, the changes in serum calcium and serum potassium levels should be monitored before, during, and after surgery.…”

Section: Discussionmentioning

confidence: 99%

“…(e.g., temporary external drains/serial lumbar punctures) [3]. For children with pure communicating hydrocephalus, the success rate was 60% in CSF shunting and 67% in ETV at the last visit [4]. For patients with non-communicating hydrocephalus, a meta-analysis reported that there was no signi cant difference in symptom improvement between ETV and ventriculoperitoneal shunting, however, ETV was associated with a lower incidence of major complications compared with ventriculoperitoneal shunting [5].…”

Section: Introductionmentioning

confidence: 99%

Analysis of the risk factors of post-operative seizure in pediatric patients with hydrocephalus undergoing endoscopic third ventriculostomy

Wang

Liu

et al. 2022

Childs Nerv Syst

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Methods: Data of pediatric patients with hydrocephalus who were treated with ETV from October 1, 2015, to November 31, 2021, were retrospectively analyzed. Basic demographic characteristics, etiology of hydrocephalus, surgical details, and laboratory measurements were collected. An early postoperative seizure was de ned as the occurrence of at least one clinical seizure within 24 h of ETV.Results: A total of 50 participants were included in the study, of whom 5 (10.00%) cases were in postoperative epilepsy group and 45 (90.00%) cases were in non-epilepsy group. Epilepsy patients were younger than those without epilepsy, while no statistically signi cant difference was found (P = 0.0836). In the age subgroup, children with epilepsy were younger than 2 years old. All patients with epilepsy received Ringer's solution intraoperatively. The mean postoperative serum calcium and potassium concentrations were signi cantly lower in patients with epilepsy than in those without epilepsy (P calcium =0.0429; P potassium = 0.0250). Moreover, a faster decrease of serum potassium and calcium levels was found in children with epilepsy compared with those without epilepsy after ETV. Conclusion:The decrease of serum calcium and potassium levels, younger age, and using Ringer's solution as irrigation uid were risk factors for epilepsy after ETV.

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“…James et al discovered that decorin possesses the ability to mitigate astrocyte hyperplasia resulting from hydrocephalus, thus offering potential therapeutic benefits for alleviating the pathological symptoms associated with this condition [ 25 ]. Furthermore, it can be effectively combined with choroidal plexus cautery to treat hydrocephalus [ 26 – 28 ].…”

Section: Introductionmentioning

confidence: 99%

A Review of Cerebrospinal Fluid Circulation and the Pathogenesis of Congenital Hydrocephalus

Zhang,

Hu,

Wang

2024

Neurochem Res

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The brain’s ventricles are filled with a colorless fluid known as cerebrospinal fluid (CSF). When there is an excessive accumulation of CSF in the ventricles, it can result in high intracranial pressure, ventricular enlargement, and compression of the surrounding brain tissue, leading to potential damage. This condition is referred to as hydrocephalus. Hydrocephalus is classified into two categories: congenital and acquired. Congenital hydrocephalus (CH) poses significant challenges for affected children and their families, particularly in resource-poor countries. Recognizing the psychological and economic impacts is crucial for developing interventions and support systems that can help alleviate the distress and burden faced by these families. As our understanding of CSF production and circulation improves, we are gaining clearer insights into the causes of CH. In this article, we will summarize the current knowledge regarding CSF circulation pathways and the underlying causes of CH. The main causes of CH include abnormalities in the FoxJ1 pathway of ventricular cilia, dysfunctions in the choroid plexus transporter Na+-K+-2Cl- contransporter isoform 1, developmental abnormalities in the cerebral cortex, and structural abnormalities within the brain. Understanding the causes of CH is indeed crucial for advancing research and developing effective treatment strategies. In this review, we will summarize the findings from existing studies on the causes of CH and propose potential research directions to further our understanding of this condition.

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Endoscopic third ventriculostomy and cerebrospinal fluid shunting for pure communicating hydrocephalus in children

Cited by 6 publications

References 28 publications

A Selection of Surgical Interventions in Pediatric Hydrocephalus

A Selection of Surgical Interventions in Pediatric Hydrocephalus

Analysis of the risk factors of post-operative seizure in pediatric patients with hydrocephalus undergoing endoscopic third ventriculostomy

A Review of Cerebrospinal Fluid Circulation and the Pathogenesis of Congenital Hydrocephalus

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