Endoscopic submucosal excavation for gastric plexiform fibromyxoma: A case report and systematic review of literature

Abstract

Plexiform fibromyxoma (PF) is a rare mesenchymal tumor of which the pathogenesis and molecular changes are still unclear. Histologically, it is characterized by a cluster of bland spindle or ovoid cells growing in the mucoid or fibromyxoid stroma rich in small blood vessels. At present, surgical resection is the primary treatment for PF.

A case of asymptomatic gastric plexiform fibromyxoma followed up for 3 years

“…This case presented an approximately 3.0 cm in diameter in the gastric antrum with a nonulcerative appearance. PF usually originates from the submucosal or muscularis propria layers and appears as mildly heterogeneous hypoechoic lesions on EUS 1 . In this case, EUS showed a hypoechoic mass located in the submucosal layer, consistent with previous reports.…”

“…The most common symptom of PF is abdominal pain, 1 but our patient did not show any symptoms. PF primarily occurs in the gastric antrum (73.2%), mostly with an ulcerated surface (70.1%) and a diameter of 2–6 cm (61.2%) 1 . This case presented an approximately 3.0 cm in diameter in the gastric antrum with a nonulcerative appearance.…”

“…PF, also known as plexiform angiomyxoid myofibroblastic tumors, was first characterized in 2007 2 . PF is often present in patients between 40–60 years of age and predominantly female 1 . In this case, a 58‐year‐old woman, was considered a typical case of PF.…”

“…Plexiform fibromyxoma (PF) is a rare mesenchymal tumor that was recently recognized and added to the Classification of Tumors of the Digestive System by the World Health Organization as a diagnostic term in 2010. PF is typically located in the gastric antrum and shows unique pathological findings, enabling differentiation from other gastric subepithelial tumors (SETs), including gastrointestinal stromal tumors 1 . Moreover, PF is benign but is usually treated surgically because of abdominal symptoms.…”

Pursestring encirclement before endoscopic submucosal excavation of a cecal submucosal tumor

“…Endoscopic submucosal excavation (ESE) has been successfully applied to the resection of gastric submucosal tumors (SMTs) 1 2 3 4 , but rarely to colonic SMTs because of the inevitability of perforation and subsequent peritonitis. The perforation is usually difficult to close quickly using titanium clips, owing to the collapse of the operational field of view, which is hard to restore by insufflation of carbon dioxide.…”