Endoscopic submucosal dissection as treatment for early gastric cancer: Experience at two centers in Lima, Peru

Vega, Juan Antonio Chirinos; Vargas, Gloria; Alcántara, C. Zepeda; Zapata, Juan Celis

doi:10.1016/j.rgmxen.2018.03.007

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…Fifteen studies reported data on the curative resection rate of superficial gastric neoplasms treated by ESD, including only adenocarcinoma histology (n=863) [ 8 , 9 , 11 , 18 , 24 , 26 , 28 - 30 , 32 , 35 - 39 ]. Curative resection including only adenocarcinoma histology was achieved in 75% overall (95%CI 0.70-0.80; I 2 =67%) ( Fig.…”

Section: Resultsmentioning

confidence: 99%

Short-term outcomes of endoscopic submucosal dissection for the treatment of superficial gastric neoplasms in non-Asian countries: a systematic review and meta-analysis

Benites-Goñi¹

2023

aog

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Background Endoscopic submucosal dissection (ESD) is now considered the standard treatment for early gastric cancer (EGC). However, the widespread adoption of ESD in western countries has been slow. We performed a systematic review to evaluate short-term outcomes of ESD for EGC in non-Asian countries. Methods We searched 3 electronic databases from inception until October 26, 2022. Primary outcomes were en bloc , R0 and curative resections rate by region. Secondary outcomes were overall complications, bleeding, and perforation rate by region. The proportion of each outcome, with the 95% confidence interval (CI), was pooled using a random-effects model with the Freeman-Tukey double arcsine transformation. Results Twenty-seven studies from Europe (n=14), South America (n=11) and North America (n=2) were included, involving 1875 gastric lesions. Overall, en bloc , R0, and curative resection rates were achieved in 96% (95%CI 94-98%), 85% (95%CI 81-89%), and 77% (95%CI 73-81%) of cases, respectively. Considering only information from lesions with adenocarcinoma, the overall curative resection was 75% (95CI 70-80%). Bleeding and perforation were observed in 5% (95%CI 4-7%) and 2% (95%CI 1-4%) of cases, respectively. Conclusion Our results suggest that short-term outcomes of ESD for the treatment of EGC are acceptable in non-Asian countries.

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Section: Resultsmentioning

confidence: 99%

Short-term outcomes of endoscopic submucosal dissection for the treatment of superficial gastric neoplasms in non-Asian countries: a systematic review and meta-analysis

Benites-Goñi¹

2023

aog

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A Single-Center Early Experience of Endoscopic Submucosal Dissection for Gastric Lesions in Thailand

Mahawongkajit

2020

Gastroenterology Research and Practice

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Endoscopic submucosal dissection (ESD) was also considered a “high risk” at the starting point with skillful endoscopic techniques and terrible complications. Still, it remains challenging yet has become widespread among institutes in many parts of the world. This study is aimed at further investigating the feasibility, efficacy, and safety of ESD of gastric lesions and at evaluating clinical outcomes in early experience. The patient characteristics, postoperative outcomes, and results of histopathological examinations were reviewed retrospectively between January 2017 and May 2019. Thirteen patients’ gastric ESD were included with all of en bloc resections without recurrence. The long duration was related to the large lesion, the upper part of the stomach, and previous treatment. In this study, the ESD procedure of the stomach is a feasible and safe minimally invasive treatment option with organ preservation. It requires training and experience with a learning approach where skill may be improved to prevent unwanted complications.

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Efficacy and Safety of Endoscopic Submucosal Dissection for Superficial Gastric Neoplasms: A Latin American Cohort Study

Palacios-Salas¹,

Benites-Goñi

Marin-Calderón

et al. 2022

Clin Endosc

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Background/Aims: Endoscopic submucosal dissection (ESD) is the preferred technique for treating early gastric cancer (EGC). However, very few studies have been conducted in South America. This study aimed to assess the efficacy and safety of ESD for EGC.Methods: We analyzed data from a prospective cohort from 2013 to 2020. A total of 152 superficial gastric neoplasms that fulfilled the absolute or expanded criteria for ESD were included. Outcomes were en bloc, R0, and curative resection rates, incidence of adverse events, and length of procedure.Results: The mean patient age was 68.4 years. The number of included patients based on the absolute and expanded indications was 150 and 2, respectively. En bloc, R0, and curative resections were achieved in 98.0%, 96.1%, and 89.5% of the cases, respectively. Bleeding and perforation were reported in 5.9% and 6.6% of the cases, respectively. Histopathological examination revealed lowgrade dysplasia, high-grade dysplasia, well-differentiated adenocarcinoma, and poorly differentiated adenocarcinoma in 13, 20, 117, and 2 cases, respectively.Conclusions: Our study shows that ESD performed by properly trained endoscopists in reference centers is safe and effective, with comparable therapeutic outcomes to those reported in the Eastern series.

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Endoscopic submucosal dissection as treatment for early gastric cancer: Experience at two centers in Lima, Peru

Cited by 3 publications

References 9 publications

Short-term outcomes of endoscopic submucosal dissection for the treatment of superficial gastric neoplasms in non-Asian countries: a systematic review and meta-analysis

Short-term outcomes of endoscopic submucosal dissection for the treatment of superficial gastric neoplasms in non-Asian countries: a systematic review and meta-analysis

A Single-Center Early Experience of Endoscopic Submucosal Dissection for Gastric Lesions in Thailand

Efficacy and Safety of Endoscopic Submucosal Dissection for Superficial Gastric Neoplasms: A Latin American Cohort Study

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