Endoscopic sinus surgery in cystic fibrosis: do patients benefit from surgery?

The Effect of Sinus Surgery with Intensive follow-up on Pathogenic Sinus Bacteria in Patients with Cystic Fibrosis

“…[5][6][7] There is no consensus on whether sinus surgery has an impact on subsequent lung infections. [8][9][10][11][12][13][14] Theoretically, bacterial eradication by sinus surgery can reduce the migration of bacteria from the upper to the lower airways, reducing morbidity. Nevertheless, whether pathogenic bacteria in CF sinuses are eligible for eradication has, to our knowledge, never been addressed in nonlung transplanted (LTX) CF patients.…”

Contribution of CT-assisted navigation and microdebriders to endoscopic sinus surgery in cystic fibrosis

“…Intranasal medication proved more effective once the nasal obstruction had been removed: having failed preoperatively, it succeeded in controlling symptoms over a fairly long (3 year) period postoperatively. Self-reported general wellbeing could not be quantified, nor could pulmonary function--which, to date, has not been proved to benefit from endoscopic sinus surgery in cystic fibrosis [6].…”

What is the optimal management of chronic rhinosinusitis in cystic fibrosis?

“…A study by Khalid et al [29] showed significant improvement in QOL measures, sinonasal outcomes and endoscopic findings following endoscopic sinus surgery in CF patients similar in magnitude to the non-CF CRS population. It has also been shown that there is a decreased rate of hospitalization in the 6 months following endoscopic sinus surgery [30]. Opening of the sinus drainage pathways allows for improved access for office debridements and penetration of topical medical management into the paranasal sinuses.…”